Introduction：Basic information about CAS 5650-20-4|Ethyl-PEG4-alcohol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Ethyl-PEG4-alcohol |
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| CAS Number | 5650-20-4 | Molecular Weight | 222.27900 |
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| Density | 1.026g/cm3 | Boiling Point | 302.2ºC at 760mmHg |
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| Molecular Formula | C10H22O5 | Melting Point | / |
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| MSDS | / | Flash Point | 136.6ºC |
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Names
| Name | 2-[2-[2-(2-ethoxyethoxy)ethoxy]ethoxy]ethanol |
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| Synonym | More Synonyms |
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Ethyl-PEG4-alcohol BiologicalActivity
| Description | Ethyl-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.026g/cm3 |
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| Boiling Point | 302.2ºC at 760mmHg |
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| Molecular Formula | C10H22O5 |
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| Molecular Weight | 222.27900 |
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| Flash Point | 136.6ºC |
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| Exact Mass | 222.14700 |
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| PSA | 57.15000 |
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| LogP | 0.06500 |
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| Index of Refraction | 1.438 |
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| InChIKey | GTAKOUPXIUWZIA-UHFFFAOYSA-N |
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| SMILES | CCOCCOCCOCCOCCO |
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Synonyms
| 3,6,9,12-Tetraoxatetradecanol |
| 3,6,9,12-Tetraoxa-1-tetradecanol |
| EINECS 227-090-6 |
| 2-(2-(2-(2-ethoxyethoxy)ethoxy)ethoxy)ethanol |
| tetra(ethylene glycol) monoethyl ether |
| 3,6,9,12-Tetraoxatetradecan-1-ol |
