CAS 1003-10-7|4-BUTYROTHIOLACTONE
Introduction：Basic information about CAS 1003-10-7|4-BUTYROTHIOLACTONE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4-BUTYROTHIOLACTONE | ||
|---|---|---|---|
| CAS Number | 1003-10-7 | Molecular Weight | 102.15500 |
| Density | 1.206g/cm3 | Boiling Point | 197.4ºC at 760mmHg |
| Molecular Formula | C4H6OS | Melting Point | 138 °C |
| MSDS | ChineseUSA | Flash Point | 87.6ºC |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | thiolan-2-one |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.206g/cm3 |
|---|---|
| Boiling Point | 197.4ºC at 760mmHg |
| Melting Point | 138 °C |
| Molecular Formula | C4H6OS |
| Molecular Weight | 102.15500 |
| Flash Point | 87.6ºC |
| Exact Mass | 102.01400 |
| PSA | 42.37000 |
| LogP | 1.04000 |
| Vapour Pressure | 0.38mmHg at 25°C |
| Index of Refraction | n20/D 1.523(lit.) |
| InChIKey | KMSNYNIWEORQDJ-UHFFFAOYSA-N |
| SMILES | O=C1CCCS1 |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1860 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 3,249,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 199 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 14,846,1971
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | 22 |
| Safety Phrases | S36 |
| RIDADR | UN3334 9 |
| RTECS | XN1930000 |
Articles8
More Articles| A Novel Synthesis of Poly(ester-alt-sulfide)s by the Ring-Opening Alternating Copolymerization of Oxiranes with gamma-Thiobutyrolactone Using Quaternary Onium Salts or Crown Ether Complexes as Catalysts. Macromolecules 31(15) , 4746-52, (1998) Poly(ester-alt-sulfide) (polymer 1) was synthesized by the alternating copolymerization of glycidyl phenyl ether (GPE) with gamma-thiobutyrolactone (TBL) catalyzed by either quaternary onium salts or ... | |
| Metabolic response against sulfur-containing heterocyclic compounds by the lignin-degrading basidiomycete Coriolus versicolor. Appl. Microbiol. Biotechnol. 58(4) , 517-26, (2002) The fungal conversions of sulfur-containing heterocyclic compounds were investigated using the lignin-degrading basidiomycete Coriolus versicolor. The fungus metabolized a series of sulfur compounds--... | |
| Mechanism of hydrolysis and aminolysis of homocysteine thiolactone. Chemistry 12(15) , 4144-52, (2006) Homocysteine thiolactone (tHcy) is deemed a risk factor for cardiovascular diseases and strokes, presumably because it acylates the side chain of protein lysine residues ("N-homocysteinylation"), ther... |
Synonyms
| Thiacyclopentan-2-one |
| EINECS 213-700-8 |
| Thiobutyrolactone |
| 2(3H)-Thiophenone,dihydro |
| 2-Oxothiolane |
| dihydrothiophen-2(3H)-one |
| 4-Butyrothiolactone |
| Tetrahydro-2-thiophenone |
| 5-oxotetrahydrothiophene |
| MFCD00005479 |
| 4-Thiobutyrolactone |
| 2-THIOPHENONE,TETRAHYDRO |
