Introduction：Basic information about CAS 100490-21-9|A7132, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | A7132 |
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| CAS Number | 100490-21-9 | Molecular Weight | 386.35200 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C19H16F2N4O3 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 6-fluoro-1-(4-fluorophenyl)-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylic acid |
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| Synonym | More Synonyms |
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A7132 BiologicalActivity
| Description | A7132 is an antibacterial agent. A7132 possess broad and potent antibacterial activity. |
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| Related Catalog | Signaling Pathways >>Anti-infection >>BacterialResearch Areas >>Infection |
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| Target | Antibacterial[1] |
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| In Vitro | A7132 (Compound 31) shows great oral activity against S. aureus NCTC 10649, E. coli Juhl and P. aeruginosa 5007 with MICs of 0.25, 0.05 and 0.39 μg/mL, respectively[1]. |
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| References | [1]. Chu DT, et al. Synthesis and structure-activity relationships of new arylfluoronaphthyridine antibacterialagents. J Med Chem. 1986 Nov;29(11):2363-9. |
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Chemical & Physical Properties
| Molecular Formula | C19H16F2N4O3 |
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| Molecular Weight | 386.35200 |
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| Exact Mass | 386.11900 |
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| PSA | 87.46000 |
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| LogP | 2.16550 |
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| InChIKey | ROMLGDPRVIVYSV-UHFFFAOYSA-N |
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| SMILES | O=C(O)c1cn(-c2ccc(F)cc2)c2nc(N3CCNCC3)c(F)cc2c1=O |
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Synonyms
| 1-p-fluorophenyl-6-fluoro-1,4-dihydro-4-oxo-7(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid |
| 6-fluoro-1-(4-fluorophenyl)-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid |
| sarafloxacin |
| A7132 |
