Introduction：Basic information about CAS 11140-99-1|Ristomycin sulfate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Ristomycin sulfate |
|---|
| CAS Number | 11140-99-1 | Molecular Weight | 2165.996 |
|---|
| Density | / | Boiling Point | / |
|---|
| Molecular Formula | C95H110N8O44.H2SO4 | Melting Point | / |
|---|
| MSDS | ChineseUSA | Flash Point | / |
|---|
Names
| Name | ristocetin sulfate salt |
|---|
| Synonym | More Synonyms |
|---|
Ristomycin sulfate BiologicalActivity
| Description | Ristomycin sulfate is a glycopeptide antibiotic isolated from Nocardia lurida[1]. |
|---|
| Related Catalog | Research Areas >>InfectionResearch Areas >>Inflammation/Immunology |
|---|
| References | [1]. M C Berndt, et al. Ristocetin-dependent reconstitution of binding of von Willebrand factor to purified human platelet membrane glycoprotein Ib-IX complex. Biochemistry. 1988 Jan 26;27(2):633-40. |
|---|
Chemical & Physical Properties
| Molecular Formula | C95H110N8O44.H2SO4 |
|---|
| Molecular Weight | 2165.996 |
|---|
| Exact Mass | 2164.628906 |
|---|
| PSA | 899.20000 |
|---|
| InChIKey | HHRPQUHYQBGHHF-ADHWPEJWSA-N |
|---|
| SMILES | COC(=O)C1NC(=O)C2NC(=O)C(NC(=O)C3NC(=O)C4NC(=O)C(NC(=O)C(N)c5ccc(O)c(c5)Oc5cc4cc(O)c5C)C(O)c4ccc(cc4)Oc4cc3cc(c4OC3OC(COC4OC(C)C(O)C(O)C4O)C(O)C(O)C3OC3OC(CO)C(O)C(O)C3OC3OCC(O)C(O)C3O)Oc3ccc(cc3)C2OC2CC(N)C(O)C(C)O2)c2ccc(O)c(c2)-c2c(OC3OC(CO)C(O)C(O)C3O)cc(O)cc21.O=S(=O)(O)O |
|---|
| Storage condition | -20°C |
|---|
Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- VJ8650000
- CHEMICAL NAME :
- Ristomycin, sulfate
- CAS REGISTRY NUMBER :
- 11140-99-1
- LAST UPDATED :
- 198903
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 660 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - excitement Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- AMBIEH Antibiotiki i Meditsinskaya Biotekhnologiya. Antibiotics and Medical Biotechnology. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.30-V.32, 1985-1987 Volume(issue)/page/year: 32,910,1987
|
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|
| Hazard Codes | Xi |
|---|
| Risk Phrases | 36/38 |
|---|
| Safety Phrases | 22-24/25-37/39-26 |
|---|
| RIDADR | UN 3249 |
|---|
| RTECS | VJ8650000 |
|---|
| Packaging Group | III |
|---|
| Hazard Class | 6.1(b) |
|---|
Articles5
More Articles
| Overproduction of Ristomycin A by activation of a silent gene cluster in Amycolatopsis japonicum MG417-CF17. Antimicrob. Agents Chemother. 58(10) , 6185-96, (2014) The emergence of antibiotic-resistant pathogenic bacteria within the last decades is one reason for the urgent need for new antibacterial agents. A strategy to discover new anti-infective compounds is... | |
| Jordan, D.C., D. Gottlieb and P. Shaw,, ed. Antibiotics New York , (1967) 1 , 84
| |
| Ristocetin- and thrombin-induced platelet aggregation at physiological shear rates: differential roles for GPIb and GPIIb-IIIa receptor. Thromb. Haemost. 80 , 428-436, (1998) We recently reported that washed platelets (WP) activated with ADP and expressing surface-bound vWF aggregated in flow through small tubes or in a cylindrical couette device at physiological shear rat... | |
Synonyms
| RISTOCETIN A SULFATE |
| Methyl (1S,2R,18R,19R,22R,34S,37R,40R)-22-amino-2-[(3-amino-2,3,6-trideoxy-α-L-ribo-hexopyranosyl)oxy]-64-{[β-D-arabinopyranosyl-(1->2)-D-mannopyranosyl-(1->2)-[6-deoxy-α-L-mannopyranosyl-( 1->6)]-β-D-glucopyranosyl]oxy}-18,26,31,44,49-pentahydroxy-47-(β-D-mannopyranosyloxy)-30-methyl-21,35,38,54,56,59-hexaoxo-7,13,28-trioxa-20,36,39,53,55,58-hexaazaundecacyclo[38.14.2.2.2.2.1.1.1.1~41, |
| Ristocetin sulfate salt |
| RISTOMYCIN MONOSULFATE |
| RISTOCETINSULFATQ |
| Ristocetin A sulphate |
| RISTOCETIN SULFATE |
| RISTOMYCIN |
| SPONTIN |
| ristomycin,sulfate |
| RISTON |
