CAS 102-50-1|4-Methoxy-2-methylaniline

Introduction：Basic information about CAS 102-50-1|4-Methoxy-2-methylaniline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
4. Safety Information
5. Customs
6. Articles1
7. Synonyms

Common Name	4-Methoxy-2-methylaniline
CAS Number	102-50-1	Molecular Weight	137.179
Density	1.0±0.1 g/cm3	Boiling Point	249.4±20.0 °C at 760 mmHg
Molecular Formula	C₈H₁₁NO	Melting Point	13-14 °C(lit.)
MSDS	ChineseUSA	Flash Point	113.5±15.0 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	2-Methyl-4-methoxybenzenamine
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.0±0.1 g/cm3
Boiling Point	249.4±20.0 °C at 760 mmHg
Melting Point	13-14 °C(lit.)
Molecular Formula	C₈H₁₁NO
Molecular Weight	137.179
Flash Point	113.5±15.0 °C
Exact Mass	137.084061
PSA	35.25000
LogP	1.20
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.549
InChIKey	CDGNLUSBENXDGG-UHFFFAOYSA-N
SMILES	COc1ccc(N)c(C)c1
Storage condition	Refrigerator
Stability	Stable. May be light or air-sensitive. Combustible. Incompatible with acids, strong oxidizing agents.
Water Solubility	insoluble,

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BZ6730000

CHEMICAL NAME :: p-Anisidine, 2-methyl-

CAS REGISTRY NUMBER :: 102-50-1

BEILSTEIN REFERENCE NO. :: 0774727

LAST UPDATED :: 199701

DATA ITEMS CITED :: 16

MOLECULAR FORMULA :: C8-H11-N-O

MOLECULAR WEIGHT :: 137.20

WISWESSER LINE NOTATION :: ZR B1 DO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 62 gm/kg/77W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 29800 mg/kg/53W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 31 gm/kg/77W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 29 mg/kg/53W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 14900 mg/kg/53W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 30800 mg/kg/77W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 61600 mg/kg/77W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors

MUTATION DATA

TYPE OF TEST :: Morphological transformation

TEST SYSTEM :: Rodent - rat Embryo

DOSE/DURATION :: 51500 ng/plate

REFERENCE :: JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 1,190,1981 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 27,91,1982 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 27,91,1982 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FRANCE;Carcinogen JAN 1993

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xn:Harmful;
Risk Phrases	R36/37/38;R40
Safety Phrases	S26-S36/37/39
RIDADR	2810
WGK Germany	3
RTECS	BZ6730000
Packaging Group	III
Hazard Class	6.1
HS Code	2922299090

Customs

HS Code	2922299090
Summary	2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles1

meta- and para-Cresidine.

IARC Monogr. Eval. Carcinog. Risk Chem. Hum. 27 , 91-101, (1982)

Synonyms

4-Methoxy-2-methyl aniline

Benzenamine, 4-methoxy-2-methyl-

EINECS 203-036-7

MFCD00007735

4-Methoxy-o-toluidine

1-Amino-4-methoxy-2-methylbenzene

4-Methoxy-2-methylaniline

m-Cresidine

2-Methyl-4-methoxyaniline

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