CAS 72178-02-0|Fomesafen
Introduction：Basic information about CAS 72178-02-0|Fomesafen, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Fomesafen | ||
|---|---|---|---|
| CAS Number | 72178-02-0 | Molecular Weight | 438.763 |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 531.4±60.0 °C at 760 mmHg |
| Molecular Formula | C15H10ClF3N2O6S | Melting Point | 220-221°C |
| MSDS | ChineseUSA | Flash Point | 275.2±32.9 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | fomesafen |
|---|---|
| Synonym | More Synonyms |
Fomesafen BiologicalActivity
| Description | Fomesafen is a type of efficient and selective protoporphyrinogen IX oxidase (PPO) inhibitor. Fomesafen is a herbicide and has the advantages of low toxicity and high selectivity[1]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| References | [1]. Li-Xia Zhao, et al. Novel Thiazole Phenoxypyridine Derivatives Protect Maize From Residual Pesticide Injury Caused by PPO-Inhibitor Fomesafen. Biomolecules. 2019 Sep 20;9(10):514. |
Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 531.4±60.0 °C at 760 mmHg |
| Melting Point | 220-221°C |
| Molecular Formula | C15H10ClF3N2O6S |
| Molecular Weight | 438.763 |
| Flash Point | 275.2±32.9 °C |
| Exact Mass | 437.990021 |
| PSA | 126.67000 |
| LogP | 3.58 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.586 |
| InChIKey | BGZZWXTVIYUUEY-UHFFFAOYSA-N |
| SMILES | CS(=O)(=O)NC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-] |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,433,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,433,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - duck
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,433,1991
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R22 |
| Safety Phrases | S2 |
| RIDADR | NONH for all modes of transport |
| RTECS | CV2475000 |
| HS Code | 2935009016 |
Customs
| HS Code | 2935009016 |
|---|---|
| Summary | 2935009016 methyl (4-aminophenyl)sulfonylcarbamate。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:35.0% |
Articles25
More Articles| The effect of protoporphyrinogen oxidase inhibitors on microsomal and mitochondrial cytochromes. Obes. Res. 3 Suppl 5 , 785S-788S, (1995) Neurological dysfunction is a characteristic feature of acute porphyrias, unexplained until now. One of the possible explanations is a deficiency of heme in the central nervous system, caused by a blo... | |
| Occurrence and distribution of sulfonylurea and related herbicides in central Canadian surface waters 2006-2008. Bull. Environ. Contam. Toxicol. 87(4) , 420-5, (2011) Surface water sampling in 2006-2008 measured the occurrence of sulfonylureas and related herbicides (SUs) during base flow conditions and wet weather events. Flumetsulam (29.2%), diuron (36.5%) and fo... | |
| Experimental hepatic uroporphyria induced by the diphenyl-ether herbicide fomesafen in male DBA/2 mice. Toxicol. Appl. Pharmacol. 189(1) , 28-38, (2003) Hepatic uroporphyria can be readily induced by a variety of treatments in mice of the C57BL strains, whereas DBA/2 mice are almost completely resistant. However, feeding of the protoporphyrinogen oxid... |
Synonyms
| 5-[2-chloro-4-(trifluoromethyl)phenoxy]-N-(methanesulfonyl)-2-nitrobenzamide |
| Benzamide, 5-[2-chloro-4-(trifluoromethyl)phenoxy]-N-(methylsulfonyl)-2-nitro- |
| 5-[2-chloro-4-(trifluoromethyl)phenoxy]-N-methylsulfonyl-2-nitrobenzamide |
| Benzenecarboximidic acid, 5-[2-chloro-4-(trifluoromethyl)phenoxy]-N-(methylsulfonyl)-2-nitro- |
| MFCD01632756 |
| EINECS 276-439-9 |
| 5-[2-Chloro-4-(trifluoromethyl)phenoxy]-N-(methylsulfonyl)-2-nitrobenzenecarboximidic acid |
| 5-(2-chloro-α,α,α-trifluoro-p-tolyloxy)-N-mesyl-2-nitrobenzamide |
| fomesafen [ANSI] |
| Fomesafen |
| 5-[2-Chloro-4-(trifluoromethyl)phenoxy]-N-(methylsulfonyl)-2-nitrobenzamide |
| WS1&MVR BNW EOR BG DXFFF |
| Fomesafene |
