CAS 88040-23-7|Cefepime

Introduction：Basic information about CAS 88040-23-7|Cefepime, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Cefepime BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	Cefepime
CAS Number	88040-23-7	Molecular Weight	480.561
Density	/	Boiling Point	/
Molecular Formula	C₁₉H₂₄N₆O₅S₂	Melting Point	150ºC
MSDS	/	Flash Point	/

Names

Name	cefepime
Synonym	More Synonyms

Cefepime BiologicalActivity

Description	Cefepime is a Cephalosporin with activity against both Gram-positive and Gram-negative aerobic bacteria. Cefepime exerts its antibacterial effects by binding to penicillin-binding proteins[1]. Cefepime has certain neurotoxicity[2].
Related Catalog	Research Areas >>Infection
Target	Gram-positive and Gram-negative aerobic bacteria[1]
References	[1]. Barradell LB, Bryson HM. Cefepime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs. 1994;47(3):471-505. [2]. B A Cunha, et al. Cefepime. Med Clin North Am. 1995 Jul;79(4):721-32. [3]. L Boschung-Pasquier, et al. Cefepime neurotoxicity: thresholds and risk factors. A retrospective cohort study. Clin Microbiol Infect. 2020 Mar;26(3):333-339.

Chemical & Physical Properties

Melting Point	150ºC
Molecular Formula	C₁₉H₂₄N₆O₅S₂
Molecular Weight	480.561
Exact Mass	480.124969
PSA	203.58000
LogP	-1.62
InChIKey	HVFLCNVBZFFHBT-CXAGYDPISA-N
SMILES	CON=C(C(=O)NC1C(=O)N2C(C(=O)[O-])=C(C[N+]3(C)CCCC3)CSC12)c1csc(N)n1

Safety Information

Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	7-16-53-45-36/37
RIDADR	UN 2924 3/PG 2
WGK Germany	3
RTECS	CX9850000
HS Code	32041300

Customs

HS Code	32041300

Synonyms

7-[(Z)-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]-3-(1-methylpyrrolidino)methyl-3-cephem-4-carboxylate

(6R,7R)-7-[2-(2-amino-4-thiazolyl)-2-(Z)-(methoxyimino)acetamido]-3-[(1-methyl-1-pyrrolidinium)methyl]-3-cephem-4-carboxylate

MFCD00864890

Pyrrolidinium, 1-[[(6R,7R)-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)-1-oxoethyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-, inner salt

[6R-[6a,7b(Z)]]-1-[[7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methylpyrrolidinium inner salt

Cefepime

Cefpim

CEFEPIME ARGININE

(6R,7R)-7-{[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(1-methyl-1-pyrrolidiniumyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Tsefepim

(6R,7R)-7-{[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(1-methylpyrrolidinium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

CFPM

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