CAS 529-53-3|Scutellarein
| Common Name | Scutellarein | ||
|---|---|---|---|
| CAS Number | 529-53-3 | Molecular Weight | 286.236 |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 642.9±55.0 °C at 760 mmHg |
| Molecular Formula | C15H10O6 | Melting Point | 330ºC |
| MSDS | ChineseUSA | Flash Point | 249.9±25.0 °C |
Names
| Name | Scutellarein |
|---|---|
| Synonym | More Synonyms |
Scutellarein BiologicalActivity
| Description | Scutellarin, a main active ingredient extracted from Erigeron breviscapus (Vant.) Hand-Mazz., has been wildly used to treat acute cerebral infarction and paralysis induced by cerebrovascular diseases. |
|---|---|
| Related Catalog | Signaling Pathways >>Autophagy >>AutophagySignaling Pathways >>Protein Tyrosine Kinase/RTK >>SrcResearch Areas >>Inflammation/ImmunologyNatural Products >>Flavonoids |
| References | [1]. Xiaoxuan Tian, et al. Delineation of Platelet Activation Pathway of Scutellarein Revealed Its Intracellular Target as Protein Kinase C. Biological and Pharmaceutical BulletinVol. 39 (2016) No. 2 p. 181-191 [2]. Sung NY, et al. Scutellarein Reduces Inflammatory Responses by Inhibiting Src Kinase Activity. Korean J Physiol Pharmacol. 2015 Sep;19(5):441-9. |
Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 642.9±55.0 °C at 760 mmHg |
| Melting Point | 330ºC |
| Molecular Formula | C15H10O6 |
| Molecular Weight | 286.236 |
| Flash Point | 249.9±25.0 °C |
| Exact Mass | 286.047729 |
| PSA | 111.13000 |
| LogP | 2.54 |
| Appearance of Characters | yellow |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.768 |
| InChIKey | JVXZRQGOGOXCEC-UHFFFAOYSA-N |
| SMILES | O=c1cc(-c2ccc(O)cc2)oc2cc(O)c(O)c(O)c12 |
| Storage condition | 2-8°C |
| Water Solubility | DMSO: soluble1mg/mL, clear, greenish-yellow |
Safety Information
| Safety Phrases | 24/25 |
|---|---|
| RIDADR | NONH for all modes of transport |
| HS Code | 2914501900 |
Customs
| HS Code | 2914501900 |
|---|---|
| Summary | 2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
Articles29
More Articles| Delineation of Platelet Activation Pathway of Scutellarein Revealed Its Intracellular Target as Protein Kinase C. Biol. Pharm. Bull. 39 , 181-91, (2016) Erigeron breviscapus has been widely used in traditional Chinese medicine (TCM) and its total flavonoid component is commonly used to treat ischemic stroke, coronary heart disease, diabetes and hypert... | |
| Liquid Chromatography-Tandem Mass Spectrometry Screening Method for the Detection of Radical-Scavenging Natural Antioxidants from the Whole Scutellariae (Radix, Stem and Leaf). J. Chromatogr. Sci. 53 , 1140-6, (2015) A novel free radical reaction combined with high-performance LC-photodiode array-ESI-MS/MS screening method was developed for the detection and identification of natural antioxidants from whole Scutel... | |
| Effect of light, methyl jasmonate and cyclodextrin on production of polyphenolic compounds in hairy root cultures of Scutellaria lateriflora Phytochemistry 107 , 50-60, (2014) Graphical abstract [Display omitted] |
Synonyms
| 4H-1-Benzopyran-4-one, 5,6,7-trihydroxy-2-(4-hydroxyphenyl)- |
| 5,6,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one |
| 5,6,7,4'-tetrahydroxyflavone |
| 5,6,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| 4',5,6,7-Tetrahydroxyflavanone |
| 6-Hydroxypelargidenon 1465 |
| Scutellarein |
