CAS 81-84-5|1,8-Naphthalic anhydride

Introduction:Basic information about CAS 81-84-5|1,8-Naphthalic anhydride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name1,8-Naphthalic anhydride
CAS Number81-84-5Molecular Weight198.174
Density1.5±0.1 g/cm3Boiling Point407.5±14.0 °C at 760 mmHg
Molecular FormulaC12H6O3Melting Point269 °C
MSDSChineseUSAFlash Point206.8±17.3 °C
Symbol
GHS07
Signal WordWarning

Names

Namenaphthalic anhydride
SynonymMore Synonyms

Chemical & Physical Properties

Density1.5±0.1 g/cm3
Boiling Point407.5±14.0 °C at 760 mmHg
Melting Point269 °C
Molecular FormulaC12H6O3
Molecular Weight198.174
Flash Point206.8±17.3 °C
Exact Mass198.031693
PSA43.37000
LogP1.75
Vapour Pressure0.0±1.0 mmHg at 25°C
Index of Refraction1.712
InChIKeyGRSMWKLPSNHDHA-UHFFFAOYSA-N
SMILESO=C1OC(=O)c2cccc3cccc1c23
Water Solubilitydecomposes

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QK5350000
CHEMICAL NAME :
1,8-Naphthalic anhydride
CAS REGISTRY NUMBER :
81-84-5
BEILSTEIN REFERENCE NO. :
0153190
LAST UPDATED :
199710
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C12-H6-O3
MOLECULAR WEIGHT :
198.18
WISWESSER LINE NOTATION :
T666 1A M CVOVJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
12340 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C253,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533580
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533580
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533580
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>2025 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 8,590,1987
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
4100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 8,590,1987
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - duck
DOSE/DURATION :
>6810 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 8,590,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 2 mg/m3;Skin JAN 1993

Safety Information

Symbol
GHS07
Signal WordWarning
Hazard StatementsH315-H319-H335
Precautionary StatementsP261-P305 + P351 + P338
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXi: Irritant;
Risk PhrasesR36/37/38
Safety PhrasesS26-S37/39-S24/25
RIDADRNONH for all modes of transport
WGK Germany2
RTECSQK5350000
Hazard Class4.1
HS Code29173980

Customs

HS Code2932999099
Summary2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles11

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1,8-Naphthalic anhydride antidote enhances the toxic effects of captan and thiram fungicides on Azospirillum brasilense cells.

Res. Microbiol. 142(9) , 1005-12, (1991)

The effects of ten fungicides, six herbicides and four insecticides on the nitrogen-fixing bacterium Azospirillum brasilense were examined. The fungicides captan and thiram were the most toxic among t...

Sensitive enantiomeric separation of aliphatic and aromatic amines using aromatic anhydrides as nonchiral derivatizing agents.

J. Chromatogr. A. 666 , 485-491, (1994)

New pre-column derivatizing reagents: phthalic anhydride, 3-nitrophthalic anhydride, diphenic anhydride, 1,8-naphthalic anhydride and diphenylmaleic anhydride have been developed for resolving chiral ...

Differential induction of cytochrome P450-mediated triasulfuron metabolism by naphthalic anhydride and triasulfuron.

Plant Physiol. 109(4) , 1483-90, (1995)

Cytochrome P450 monooxygenases play paramount roles in the detoxification of herbicides as well as in the synthesis of lignins, flavonoids, and phenolic acids. Biochemical analysis of triasulfuron met...

Synonyms

1H,3H-Benzo[de]isochromene-1,3-dione
1,8-naphthalene dicarboxylic anhydride
1H,3H-naphtho [1,8-cd]pyran-1,3-dione
Protect
naphthalic
1,8-naphthalic anhydride
MFCD00006925
NAPHTHALIC ANHYDRIDE
PROTECT(R)
naphthalene-1,8-dicarboxylic acid anhydride
1H,3H-Naphtho[1,8-cd]pyran-1,3-dione
1,8-Naphthalic
EINECS 201-380-2
1,8-Naphthalenedicarboxylic acid anhydride
pakarli
naphthalene-1,8-dicarboxylic anhydride
1,8-dinaphthoic anhydride
1H,3H-Naphtho(1,8-cd)pyran-1,3-dione (9CI)
1,8-Naphthalic anhyd
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