CAS 68-96-2|17α-hydroxyprogesterone

Introduction：Basic information about CAS 68-96-2|17α-hydroxyprogesterone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Articles61
6. Synonyms

Common Name	17α-hydroxyprogesterone
CAS Number	68-96-2	Molecular Weight	330.461
Density	1.2±0.1 g/cm3	Boiling Point	482.9±45.0 °C at 760 mmHg
Molecular Formula	C₂₁H₃₀O₃	Melting Point	276°C
MSDS	ChineseUSA	Flash Point	260.0±25.2 °C
Symbol	GHS02, GHS06, GHS08	Signal Word	Danger

Names

Name	17α-hydroxyprogesterone
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	482.9±45.0 °C at 760 mmHg
Melting Point	276°C
Molecular Formula	C₂₁H₃₀O₃
Molecular Weight	330.461
Flash Point	260.0±25.2 °C
Exact Mass	330.219482
PSA	54.37000
LogP	2.89
Vapour Pressure	0.0±2.8 mmHg at 25°C
Index of Refraction	1.560
InChIKey	DBPWSSGDRRHUNT-CEGNMAFCSA-N
SMILES	CC(=O)C1(O)CCC2C3CCC4=CC(=O)CCC4(C)C3CCC21C
Storage condition	-20?C Freezer

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TU5060000

CHEMICAL NAME :: Pregn-4-ene-3,20-dione, 17-hydroxy-

CAS REGISTRY NUMBER :: 68-96-2

BEILSTEIN REFERENCE NO. :: 2062088

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C21-H30-O3

MOLECULAR WEIGHT :: 330.51

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

DOSE :: 65 mg/kg

SEX/DURATION :: female 8-32 week(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - gastrointestinal system Reproductive - Specific Developmental Abnormalities - urogenital system

REFERENCE :: PEDIAU Pediatrics. (American Academy of Pediatrics, P.O. Box 1034, Evanston, IL 60204) V.1- 1948- Volume(issue)/page/year: 26,151,1960

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 5 mg/kg

SEX/DURATION :: female 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - other measures of fertility

REFERENCE :: ACEDAB Acta Endocrinologica, Supplementum (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) No.1- 1948- Volume(issue)/page/year: 28,18,1956

Safety Information

Symbol	GHS02, GHS06, GHS08
Signal Word	Danger
Hazard Statements	H225-H301 + H311 + H331-H370
Precautionary Statements	P210-P260-P280-P301 + P310-P311
Personal Protective Equipment	Eyeshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T: Toxic;
Risk Phrases	61
Safety Phrases	S53-S22-S36/37/39-S45
RIDADR	2811.0
WGK Germany	3
RTECS	TU5060000

Articles61

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...

An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin.

J. Med. Chem. 51 , 2047-56, (2008)

A benchmark data set of steroids with known affinity for sex hormone-binding globulin (SHBG) has been widely used to validate popular molecular field-based QSAR techniques. We have expanded the data s...

Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Nat. Chem. Biol. 5 , 765-71, (2009)

Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened...

Synonyms

17α-Hydroxypregn-4-ene-3,20-dione

17-Hydroxypregn-4-en-3,20-dione

MFCD00003659

hydroxyprogesteronum [INN_la]

17-Hydroxypregn-4-ene-3,20-dione

4-Pregnen-17a-ol-3,20-dione

4-Pregnen-17α-ol-3,20-dione

17alpha-hydroxyprogesterone

Pregn-4-ene-3,20-dione, 17-hydroxy-

17α-Hydroxyprogesterone

Gestageno

L E5 B666 OV MUTJ A1 E1 FV1 FQ &&17α

EINECS 200-699-4

17a-Hydroxypregn-4-ene-3,20-dione

17A-hydroxyprogesterone

17-Hydroxyprogesterone

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