CAS 100111-07-7|GnRH Associated Peptide: GAP: 1-13, human

Introduction：Basic information about CAS 100111-07-7|GnRH Associated Peptide: GAP: 1-13, human, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Articles2
6. Synonyms

Common Name	GnRH Associated Peptide: GAP: 1-13, human
CAS Number	100111-07-7	Molecular Weight	1492.58000
Density	/	Boiling Point	/
Molecular Formula	C₆₅H₁₀₁N₁₅O₂₅	Melting Point	/
MSDS	ChineseUSA	Flash Point	/

Names

Name	GnRH Associated Peptide: GAP: 1-13, human
Synonym	More Synonyms

BiologicalActivity

Description	GnRH Associated Peptide (GAP) (1-13), human is an amino acid peptide fragment derived from GnRH. GAP can increase the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in rat anterior pituitary cells. GAP also inhibit the secretion of prolactin[1].
Related Catalog	Signaling Pathways >>GPCR/G Protein >>GNRH ReceptorResearch Areas >>Endocrinology
Target	LH, FSH, Prolactin[1]

Chemical & Physical Properties

Molecular Formula	C₆₅H₁₀₁N₁₅O₂₅
Molecular Weight	1492.58000
Exact Mass	1491.71000
PSA	668.13000
LogP	0.87670
InChIKey	SLLIDJFLMJLJIA-CXWSTQGDSA-N
SMILES	CCC(C)C(NC(=O)C(CC(C)C)NC(=O)C(CC(N)=O)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(N)CC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)NC(Cc1ccccc1)C(=O)NC(CCC(N)=O)C(=O)NC(CCC(=O)O)C(=O)NC(C(=O)NC(C(=O)O)C(C)C)C(C)CC

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport

Articles2

Stimulation of gonadotropin release by a non-GnRH peptide sequence of the GnRH precursor.

Science 232 , 68, (1986)

The human gonadotropin-releasing hormone (GnRH) precursor comprises the GnRH sequence followed by an extension of 59 amino acids. Basic amino acid residues in the carboxyl terminal extension may repre...

LH-releasing activity and receptor binding of pHGnRH 14-26 analogues.

Biochem. Biophys. Res. Commun. 143(3) , 872-9, (1987)

The human gonadotropin-releasing hormone (GnRH) precursor consists of the GnRH sequence followed by a cleavage and amidation site and a 56-amino acid carboxyl-terminal extension (pHGnRH - precursor hu...

Synonyms

Gn-RH Associated Peptide (GAP) (1-13),human

GNRH ASSOCIATED PEPTIDE (1-13),HUMAN

Asp-Al-Glu-Asn-Leu-Ile-Asp-Ser-Phe-Gln-Glu-Ile-Val

GNRH precursor (14-26)

GAP (1-13) (HUMAN)

PREPRO HUMAN GNRH PRECURSOR PEPTIDE (14-26)

GAP (1-13)

GNRH PRECURSOR PEPTIDE (14-26) (HUMAN)

GNRH PRECURSOR (14-26),RAT

asp-ala-glu-asn-leu-ile-asp-ser-phe-*gln-glu-ile

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