Introduction：Basic information about CAS 93674-99-8|H-Arg-Gly-Asp-Val-OH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | H-Arg-Gly-Asp-Val-OH |
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| CAS Number | 93674-99-8 | Molecular Weight | 445.47100 |
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| Density | 1.57g/cm3 | Boiling Point | 821.1ºC at 760 mmHg |
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| Molecular Formula | C17H31N7O7 | Melting Point | / |
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| MSDS | / | Flash Point | 450.4ºC |
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Names
| Name | (2S)-2-[[(2S)-2-[[2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]-3-methylbutanoic acid |
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| Synonym | More Synonyms |
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H-Arg-Gly-Asp-Val-OH BiologicalActivity
| Description | RGDV is a platelet aggregation inhibitor. RGDV inhibits platelet-dependent thrombus formation. RGDV is used for tumor recognition via the targeting effect[1][2]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
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| In Vitro | RGDV (25-100 nM; thrombus vessel model) selectively inhibits platelet-dependent thrombus formation and decreases the accumulation of both platelets and fibrin on the collagen substrate in a dose-response manner[1]. |
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| References | [1]. Cadroy Y, et, al. RGDV peptide selectively inhibits platelet-dependent thrombus formation in vivo. Studies using a baboon model. J Clin Invest. 1989 Sep;84(3):939-44. [2]. Wang F, et, al. Preparation and biological evaluation of tumor-specific Ara-C liposomal preparations containing RGDV motif. J Pharm Sci. 2012 Dec;101(12):4559-68. |
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Chemical & Physical Properties
| Density | 1.57g/cm3 |
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| Boiling Point | 821.1ºC at 760 mmHg |
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| Molecular Formula | C17H31N7O7 |
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| Molecular Weight | 445.47100 |
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| Flash Point | 450.4ºC |
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| Exact Mass | 445.22800 |
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| PSA | 249.82000 |
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| Index of Refraction | 1.644 |
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| InChIKey | MDNRBNZIOBQHHK-KWBADKCTSA-N |
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| SMILES | CC(C)C(NC(=O)C(CC(=O)O)NC(=O)CNC(=O)C(N)CCCN=C(N)N)C(=O)O |
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Synonyms
| Rgdv tetrapeptide |
| Arg-gly-asp-val |
| Arginyl-glycyl-aspartyl-valine |
| L-Arginylglycyl-L-alpha-Aspartyl-L-Valine |
