Introduction：Basic information about CAS 90301-60-3|5-(2-HYDROXYETHYL)-2'-DEOXYURIDINE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 5-(2-HYDROXYETHYL)-2'-DEOXYURIDINE |
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| CAS Number | 90301-60-3 | Molecular Weight | 272.25 |
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| Density | 1.496g/cm3 | Boiling Point | / |
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| Molecular Formula | C11H16N2O6 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 5-(2-hydroxyethyl)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
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5-(2-HYDROXYETHYL)-2'-DEOXYURIDINE BiologicalActivity
| Description | 5-(2-Hydroxyethyl)-2’-deoxy uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 1.496g/cm3 |
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| Molecular Formula | C11H16N2O6 |
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| Molecular Weight | 272.25 |
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| Exact Mass | 272.10100 |
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| PSA | 124.78000 |
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| Index of Refraction | 1.597 |
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| InChIKey | SORQWSCHVYGEPE-DJLDLDEBSA-N |
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| SMILES | O=c1[nH]c(=O)n(C2CC(O)C(CO)O2)cc1CCO |
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