CAS 3868-36-8|8-(Phenylmethoxy)guanosine

Introduction:Basic information about CAS 3868-36-8|8-(Phenylmethoxy)guanosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name8-(Phenylmethoxy)guanosine
CAS Number3868-36-8Molecular Weight389.36
Density1.8g/cm3Boiling Point772ºC at 760mmHg
Molecular FormulaC17H19N5O6Melting Point/
MSDS/Flash Point420.7ºC

Names

Name8-Benzyloxyguanosine
SynonymMore Synonyms

8-(Phenylmethoxy)guanosine BiologicalActivity

Description8-(Phenylmethoxy)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog
References

[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.  

Chemical & Physical Properties

Density1.8g/cm3
Boiling Point772ºC at 760mmHg
Molecular FormulaC17H19N5O6
Molecular Weight389.36
Flash Point420.7ºC
Exact Mass389.13400
PSA168.74000
Index of Refraction1.796
InChIKeyRNSGUQLXDMZREX-SDBHATRESA-N
SMILESNc1nc2c(nc(OCc3ccccc3)n2C2OC(CO)C(O)C2O)c(=O)[nH]1

Synonyms

8-Benzyloxy-guanosin
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