Introduction：Basic information about CAS 27523-40-6|Isoconazole, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Isoconazole |
|---|
| CAS Number | 27523-40-6 | Molecular Weight | 416.129 |
|---|
| Density | 1.4±0.1 g/cm3 | Boiling Point | 555.1±50.0 °C at 760 mmHg |
|---|
| Molecular Formula | C18H14Cl4N2O | Melting Point | / |
|---|
| MSDS | / | Flash Point | 289.5±30.1 °C |
|---|
Names
| Name | 1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]imidazole |
|---|
| Synonym | More Synonyms |
|---|
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|
| Boiling Point | 555.1±50.0 °C at 760 mmHg |
|---|
| Molecular Formula | C18H14Cl4N2O |
|---|
| Molecular Weight | 416.129 |
|---|
| Flash Point | 289.5±30.1 °C |
|---|
| Exact Mass | 413.986023 |
|---|
| PSA | 27.05000 |
|---|
| LogP | 5.93 |
|---|
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
|---|
| Index of Refraction | 1.625 |
|---|
| InChIKey | MPIPASJGOJYODL-UHFFFAOYSA-N |
|---|
| SMILES | Clc1ccc(C(Cn2ccnc2)OCc2c(Cl)cccc2Cl)c(Cl)c1 |
|---|
| Storage condition | 2-8°C |
|---|
| Water Solubility | Practically insoluble in water, very soluble in methanol, freely soluble in ethanol (96 per cent). |
|---|
Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- NI4775700
- CHEMICAL NAME :
- 1H-Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,6-dichlorophenyl)meth oxy)ethyl)-
- CAS REGISTRY NUMBER :
- 27523-40-6
- LAST UPDATED :
- 199303
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C18-H14-Cl4-N2-O
- MOLECULAR WEIGHT :
- 416.14
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 189 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 13,195,1990
|
Articles25
More Articles
| Tinea corporis of the shin and chest successfully treated with a topical antifungal and corticosteroid cream. Mycoses 51 Suppl 4 , 34-6, (2008)
| |
| The effective use of isoconazole nitrate and diflucortolone valerate cream in the treatment of inguino-femoral skin fold mycosis. Mycoses 51 Suppl 4 , 29-31, (2008)
| |
| Treatment of candidal intertrigo with a topical combination of isoconazole nitrate and diflucortolone valerate. Mycoses 51 Suppl 4 , 42-3, (2008)
| |
Synonyms
| Travogyn |
| Isoconazol |
| 1-[2-(2,4-Dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-1H-imidazole |
| Travogen |
| 1-{2-[(2,6-Dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole |
| 1-{2-[(2,6-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}imidazole |
| fazol |
| Isoconazole |
| 1H-Imidazole, 1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]- |
| 1-[2,4-Dichloro-b-[(2,6-dichlorobenzyl)oxy]phenethyl]imidazole |
| Isoconazolum |
