CAS 178603-73-1|Biotinyl-Asp-Glu-Val-Asp-aldehyde (pseudo acid)

Introduction:Basic information about CAS 178603-73-1|Biotinyl-Asp-Glu-Val-Asp-aldehyde (pseudo acid), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameBiotinyl-Asp-Glu-Val-Asp-aldehyde (pseudo acid)
CAS Number178603-73-1Molecular Weight686.73100
Density1.367 g/cm3Boiling Point1208.6ºC at 760 mmHg
Molecular FormulaC28H42N6O12SMelting Point/
MSDS/Flash Point684.7ºC

Names

Name(4S)-4-[[(2S)-2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]-3-carboxypropanoyl]amino]-5-[[(2S)-1-[[(2S)-1-carboxy-3-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid

BiologicalActivity

DescriptionBiotin-DEVD-CHO can be used for affinity labeling of Caspase-8 following in vitro caspase cleavage[1].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Apoptosis >>Caspase
References

[1]. Sohn D, et al. Caspase-8 can be activated by interchain proteolysis without receptor-triggered dimerization during drug-induced apoptosis. J Biol Chem. 2005;280(7):5267-5273.  

Chemical & Physical Properties

Density1.367 g/cm3
Boiling Point1208.6ºC at 760 mmHg
Molecular FormulaC28H42N6O12S
Molecular Weight686.73100
Flash Point684.7ºC
Exact Mass686.25800
PSA311.80000
LogP0.54170
Vapour Pressure0mmHg at 25°C
Index of Refraction1.558
InChIKeyNOYOANDLKBWUGA-AUJWPLEISA-N
SMILESCC(C)C(NC(=O)C(CCC(=O)O)NC(=O)C(CC(=O)O)NC(=O)CCCCC1SCC2NC(=O)NC21)C(=O)NC(C=O)CC(=O)O
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