CAS 76-54-0|dichlorofluorescein
| Common Name | dichlorofluorescein | ||
|---|---|---|---|
| CAS Number | 76-54-0 | Molecular Weight | 401.196 |
| Density | 1.8±0.1 g/cm3 | Boiling Point | 634.4±55.0 °C at 760 mmHg |
| Molecular Formula | C20H10Cl2O5 | Melting Point | 280 °C (dec.)(lit.) |
| MSDS | ChineseUSA | Flash Point | 337.4±31.5 °C |
| Symbol | GHS02, GHS07 | Signal Word | Danger |
Names
| Name | 2',7'-dichlorofluorescein |
|---|---|
| Synonym | More Synonyms |
dichlorofluorescein BiologicalActivity
| Description | 2',7'-Dichlorofluorescein acts as a fluorescent probe (Ex=496 nm and Em=525 nm) for reactive oxygen species (ROS) measurement[1]. |
|---|---|
| Related Catalog | Research Areas >>Cancer |
| References | [1]. Reiniers MJ, et al. Preparation and Practical Applications of 2',7'-Dichlorodihydrofluorescein in Redox Assays. Anal Chem. 2017 Apr 4;89(7):3853-3857. [2]. Xiuping Chen, et al. 2',7'-Dichlorodihydrofluorescein as a fluorescent probe for reactive oxygen species measurement: Forty years of application and controversy. Free Radic Res. 2010 Jun;44(6):587-604. |
Chemical & Physical Properties
| Density | 1.8±0.1 g/cm3 |
|---|---|
| Boiling Point | 634.4±55.0 °C at 760 mmHg |
| Melting Point | 280 °C (dec.)(lit.) |
| Molecular Formula | C20H10Cl2O5 |
| Molecular Weight | 401.196 |
| Flash Point | 337.4±31.5 °C |
| Exact Mass | 399.990540 |
| PSA | 75.99000 |
| LogP | 4.10 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.797 |
| InChIKey | VFNKZQNIXUFLBC-UHFFFAOYSA-N |
| SMILES | O=C1OC2(c3cc(Cl)c(O)cc3Oc3cc(O)c(Cl)cc32)c2ccccc21 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
Safety Information
| Symbol | GHS02, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H225-H319-H336 |
| Precautionary Statements | P210-P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | UN 1219 3/PG 2 |
| WGK Germany | 3 |
| RTECS | NT8050000 |
| Hazard Class | 3.0 |
| HS Code | 3204200000 |
Customs
| HS Code | 2932999099 |
|---|---|
| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 2',7'-dichloro-3',6'-dihydroxy- |
| EINECS 200-968-6 |
| dichlorofluorescein |
| 2',7'-dichloro-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one |
| 2',7'-Dichloro-3',6'-dihydroxy-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one |
| Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 2',7'-dichloro-3',6'-dihydroxy- |
| 2‘,7‘-Dichlorofluorescein |
| MFCD00005047 |
