CAS 52434-75-0|LHRH (1-5) (free acid) trifluoroacetate salt

Introduction:Basic information about CAS 52434-75-0|LHRH (1-5) (free acid) trifluoroacetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameLHRH (1-5) (free acid) trifluoroacetate salt
CAS Number52434-75-0Molecular Weight702.71
Density/Boiling Point/
Molecular FormulaC34H38N8O9Melting Point/
MSDS/Flash Point/

Names

Namelhrh (1-5)
SynonymMore Synonyms

BiologicalActivity

DescriptionLHRH (1-5) (free acid) is a polypeptide generated by the cleavage of LHRH at the Tyr55-Gly66 site. LHRH (1-5) (free acid) is converted into LHRH (1-3) and LHRH (4-5) fragments under the catalysis of Angiotensin-converting enzyme (HY-P2983)[1][2].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
References

[1]. McDermott JR, et al. Mechanism of degradation of LH-RH and neurotensin by synaptosomal peptidases. Peptides. 1983 Jan-Feb;4(1):25-30.  

[2]. Yokosawa H, et al. Degradation of luteinizing hormone-releasing hormone by neuroblastoma cells and their membrane: evidence for the involvement of a thiol protease and angiotensin-converting enzyme. J Neurochem. 1987 Jan;48(1):293-8.  

Chemical & Physical Properties

Molecular FormulaC34H38N8O9
Molecular Weight702.71
Exact Mass702.27600
PSA267.73000
LogP0.81160
InChIKeyDIBPZIVVSFXPFR-BGLOPPNPSA-N
SMILESO=C(O)C(F)(F)F.O=C1CCC(C(=O)NC(Cc2cnc[nH]2)C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)NC(CO)C(=O)NC(Cc2ccc(O)cc2)C(=O)O)N1

Synonyms

pglu-his-trp-ser-tyr
pyr-his-trp-ser-tyr-oh
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