CAS 3233-32-7|4-Acetoxyphenol

Introduction:Basic information about CAS 3233-32-7|4-Acetoxyphenol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name4-Acetoxyphenol
CAS Number3233-32-7Molecular Weight152.14700
Density1.212g/cm3Boiling Point269.3ºC at 760 mmHg
Molecular FormulaC8H8O3Melting Point/
MSDS/Flash Point118.6ºC

Names

Name4-hydroxyphenyl acetate
SynonymMore Synonyms

4-Acetoxyphenol BiologicalActivity

Description4-Hydroxyphenyl acetate (4-HPA) is a natural antioxidant and protects cells from oxidative stress-induced necrosis. 4-Hydroxyphenyl acetate blocks the increase of cellular ROS induced by oxidative stress, and up-regulates NQO1 and HO-1 genes by stabilizing and inducing the nuclear translocation of NRF2 transcription factor[1].
Related CatalogResearch Areas >>Others
Target

Human Endogenous Metabolite

In Vitro4-Hydroxyphenyl acetate (5 μM; 24 h) protects retinal pigment epithelial (RPE) cells from oxidative stress-induced cell death[1]. 4-Hydroxyphenyl acetate (5 μM; 24 h; ARPE-19 cells) inhibits the increase of ROS in response to oxidative stress and up-regulated the expression of cytoprotective genes including NQO1 and HO-1 genes[1]. Cell Viability Assay[1] Cell Line: ARPE-19 cells Concentration: 5 μM Incubation Time: 24 hours Result: Protected up to 89%, 92%, and 90% of ARPE-19 cells exposed to 100, 200, and 300 μM tBHP, respectively.

Chemical & Physical Properties

Density1.212g/cm3
Boiling Point269.3ºC at 760 mmHg
Molecular FormulaC8H8O3
Molecular Weight152.14700
Flash Point118.6ºC
Exact Mass152.04700
PSA46.53000
LogP1.31750
Index of Refraction1.541
InChIKeyHBMCQTHGYMTCOF-UHFFFAOYSA-N
SMILESCC(=O)Oc1ccc(O)cc1
Storage condition2-8°C

Safety Information

Hazard CodesXi

Synonyms

p-acetoxyphenol
p-hydroxyphenyl acetate
4-Acetoxyphenol
1,4-Benzenediol,monoacetate
(4-hydroxyphenyl) acetate
hydroquinone acetate
4-hydroxyphenylacetat
4-Hydroxyphenyl acetate
hydroquinone monoacetate
CAS 37522-02-4|p-Hydroxyphenyl dimethylcarbamate
CAS 573674-19-8|1-Naphthalenecarboxylic acid, 4-hydroxyphenyl ester
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