CAS 178928-70-6|prothioconazole
| Common Name | prothioconazole | ||
|---|---|---|---|
| CAS Number | 178928-70-6 | Molecular Weight | 344.259 |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 486.7±55.0 °C at 760 mmHg |
| Molecular Formula | C14H15Cl2N3OS | Melting Point | 139.1-144.5° |
| MSDS | ChineseUSA | Flash Point | 248.2±31.5 °C |
| Symbol | GHS09 | Signal Word | Warning |
Names
| Name | prothioconazole |
|---|---|
| Synonym | More Synonyms |
prothioconazole BiologicalActivity
| Description | Prothioconazole is a triazolinthione fungicide. Prothioconazole is a CYP51 inhibitor[1]. |
|---|---|
| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Metabolic Enzyme/Protease >>Cytochrome P450Signaling Pathways >>Anti-infection >>Fungal |
| Target | CYP51[1] |
| References | [1]. Parker JE, et al. Prothioconazole and prothioconazole-desthio activities against Candida albicans sterol 14-α-demethylase. Appl Environ Microbiol. 2013 Mar;79(5):1639-45. |
Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 486.7±55.0 °C at 760 mmHg |
| Melting Point | 139.1-144.5° |
| Molecular Formula | C14H15Cl2N3OS |
| Molecular Weight | 344.259 |
| Flash Point | 248.2±31.5 °C |
| Exact Mass | 343.031281 |
| PSA | 85.93000 |
| LogP | 1.77 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.698 |
| InChIKey | MNHVNIJQQRJYDH-UHFFFAOYSA-N |
| SMILES | OC(Cc1ccccc1Cl)(Cn1[nH]cnc1=S)C1(Cl)CC1 |
Safety Information
| Symbol | GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H410 |
| Precautionary Statements | P273-P501 |
| Personal Protective Equipment | Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant;N: Dangerous for the environment; |
| Risk Phrases | 51/53 |
| Safety Phrases | 61 |
| RIDADR | UN3077 9/PG 3 |
Articles4
More Articles| High-performance liquid chromatographic separations of stereoisomers of chiral basic agrochemicals with polysaccharide-based chiral columns and polar organic mobile phases. J. Sep. Sci. 38 , 4173-9, (2016) The separation of the stereoisomers of 23 chiral basic agrochemicals was studied on six different polysaccharide-based chiral columns in high-performance liquid chromatography with various polar organ... | |
| Triazole fungicides can induce cross-resistance to medical triazoles in Aspergillus fumigatus. PLoS ONE 7(3) , e31801, (2012) Azoles play an important role in the management of Aspergillus diseases. Azole resistance is an emerging global problem in Aspergillus fumigatus, and may develop through patient therapy. In addition, ... | |
| Exposure reduction of seed treatments through dehusking behaviour of the wood mouse (Apodemus sylvaticus). Environ. Sci. Pollut. Res. Int. 18 , 31-7, (2011) Seed treatments are widely used on cereals and other annual crops throughout Europe. Most of the formulated pesticide is found on the outside of the seed, the husk. Risk assessments of seed treatments... |
Synonyms
| T5MYNNJ BUS C1XQ1R BG&- AL3TJ |
| rac-2-[(2R)-2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazole-3-thione |
| 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazole-3-thione |
| prothioconazole |
| 2-(2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1,2-dihydro-3H-1,2,4-triazole-3-thione |
| Redigo |
| (RS)-2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-1,2,4-triazole-3-thione |
| 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-3H-1,2,4-triazole-3-thione |
| 2-(1-chloro-cyclopropyl)-1-(2-chlorophenyl)-3-(5-mercapto-1,2,4-triazol-1-yl)-propan-2-ol |
| 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2,4-triazole-3-thione |
| UNII-27B9FV58IY |
| 3H-1,2,4-Triazole-3-thione, 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro- |
| Prothioconazole [ISO:BSI] |
