CAS 105956-99-8|clinafloxacin hydrochloride

Introduction：Basic information about CAS 105956-99-8|clinafloxacin hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. clinafloxacin hydrochloride BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	clinafloxacin hydrochloride
CAS Number	105956-99-8	Molecular Weight	402.247
Density	1.573 g/cm3	Boiling Point	592.3ºCat 760 mmHg
Molecular Formula	C₁₇H₁₈Cl₂FN₃O₃	Melting Point	162-168°C
MSDS	/	Flash Point	312ºC

Names

Name	Clinafloxacin Hydrochloride
Synonym	More Synonyms

clinafloxacin hydrochloride BiologicalActivity

Description	Clinafloxacin hydrochloride (AM 1091 hydrochloride) is a potent and broad-spectrum fluoroquinolone antibiotic, with activity against gram-positive, gram-negative, and anaerobic pathogens in vitro. Clinafloxacin exhibits activity against S. pneumonia with an MIC of 1μg/ml for the parC-gyrA mutants[1][2].
Related Catalog	Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial
Target	MIC: 1μg/ml (parC-gyrA mutants,S. pneumonia)[1]
References	[1]. Pan, X.S. and L.M. Fisher, DNA gyrase and topoisomerase IV are dual targets of clinafloxacin action in Streptococcus pneumoniae. Antimicrob Agents Chemother, 1998. 42(11): p. 2810-6. [2]. Jorgensen, J.H., et al., Activities of clinafloxacin, gatifloxacin, gemifloxacin, and trovafloxacin against recent clinical isolates of levofloxacin-resistant Streptococcus pneumoniae. Antimicrob Agents Chemother, 2000. 44(11): p. 2962-8.

Chemical & Physical Properties

Density	1.573 g/cm3
Boiling Point	592.3ºCat 760 mmHg
Melting Point	162-168°C
Molecular Formula	C₁₇H₁₈Cl₂FN₃O₃
Molecular Weight	402.247
Flash Point	312ºC
Exact Mass	401.070923
PSA	88.56000
LogP	3.93180
InChIKey	BMACYHMTJHBPOX-UHFFFAOYSA-N
SMILES	Cl.NC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2Cl)C1
Storage condition	Refrigerator

Synonyms

7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid,hydrochloride

7-(3-Aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride (1:1)

7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (1:1)

3-Quinolinecarboxylic acid, 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, hydrochloride (1:1)

Clinafloxacin HCl

clinafloxacin hydrochloride

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