CAS 5216-25-1|p-Chlorobenzotrichloride

Introduction：Basic information about CAS 5216-25-1|p-Chlorobenzotrichloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Synonyms

Common Name	p-Chlorobenzotrichloride
CAS Number	5216-25-1	Molecular Weight	229.919
Density	1.5±0.1 g/cm3	Boiling Point	245.0±0.0 °C at 760 mmHg
Molecular Formula	C₇H₄Cl₄	Melting Point	5.8 °C
MSDS	/	Flash Point	109.9±23.3 °C

Names

Name	4-Chlorobenzotrichloride
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.5±0.1 g/cm3
Boiling Point	245.0±0.0 °C at 760 mmHg
Melting Point	5.8 °C
Molecular Formula	C₇H₄Cl₄
Molecular Weight	229.919
Flash Point	109.9±23.3 °C
Exact Mass	227.906708
LogP	3.94
Vapour Pressure	0.0±0.4 mmHg at 25°C
Index of Refraction	1.571
InChIKey	LVZPKYYPPLUECL-UHFFFAOYSA-N
SMILES	Clc1ccc(C(Cl)(Cl)Cl)cc1
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.
Water Solubility	decomposes

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XT8580000

CHEMICAL NAME :: Toluene, alpha,alpha,alpha,p-tetrachloro-

CAS REGISTRY NUMBER :: 5216-25-1

BEILSTEIN REFERENCE NO. :: 1866549

LAST UPDATED :: 199710

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C7-H4-Cl4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 820 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - chromodacryorrhea Behavioral - tremor Gastrointestinal - hypermotility, diarrhea

REFERENCE :: EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0281-0360

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 125 mg/m3

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 28(6),41,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 700 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay)

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 28(6),41,1984

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 125 mg/m3

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 28(6),41,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0281-0360 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 9670 ug/m3/17W-I

TOXIC EFFECTS :: Blood - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 28(6),41,1984

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 94500 ug/m3/6H/30D-I

TOXIC EFFECTS :: Blood - changes in erythrocyte (RBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0526145

Safety Information

Hazard Codes	T:Toxic;
Risk Phrases	R21/22;R37/38;R45;R48/23;R62
Safety Phrases	S53-S45
RIDADR	UN 1760 8/PG 2
WGK Germany	3
RTECS	XT8580000
Packaging Group	II
Hazard Class	8
HS Code	2903999090

Customs

HS Code	2903999090
Summary	2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Synonyms

4-Chlorbenzotrichlorid

Tetrachlorotoluene

1-Chloro-4-(trichloromethyl)benzene

α,α,α-trichloro-4-chlorotoluene

p-chlorotrichloromethylbenzene

PCTC

P-CHLOROBENZOTRICHLORIDE

P-CHLORO BENOTRICHLORIDE

4-chloro-trichloromethylbenzene

Benzene, 1-chloro-4-(trichloromethyl)-

p-Chlorbenzotrichlorid

9-chloro-1,1,1-trichloromethylbenzene

4-Chlorobenzotrichlo

α,α,α,4-Tetrachlorotoluene

p-Chlorotrichlorotoluene

EINECS 226-009-1

Toluene, p,α,α,α-tetrachloro-

MFCD00000790

4-chlorobenzotrichlorid

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