CAS 105-45-3|Methyl acetoacetate
Introduction：Basic information about CAS 105-45-3|Methyl acetoacetate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Methyl acetoacetate | ||
|---|---|---|---|
| CAS Number | 105-45-3 | Molecular Weight | 116.115 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 169.4±8.0 °C at 760 mmHg |
| Molecular Formula | C5H8O3 | Melting Point | -28 °C |
| MSDS | ChineseUSA | Flash Point | 61.6±18.5 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | Methyl acetoacetate |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 169.4±8.0 °C at 760 mmHg |
| Melting Point | -28 °C |
| Molecular Formula | C5H8O3 |
| Molecular Weight | 116.115 |
| Flash Point | 61.6±18.5 °C |
| Exact Mass | 116.047340 |
| PSA | 43.37000 |
| LogP | 0.19 |
| Vapour Pressure | 1.5±0.3 mmHg at 25°C |
| Index of Refraction | 1.399 |
| InChIKey | WRQNANDWMGAFTP-UHFFFAOYSA-N |
| SMILES | COC(=O)CC(C)=O |
| Storage condition | 2-8°C |
| Water Solubility | 460 g/L (20 ºC) |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Open irritation test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 30,63,1948
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,815,1978
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- Volume(issue)/page/year: 29,1363,1946 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3228 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 30,63,1948 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84355 No. of Facilities: 23 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 270 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84355 No. of Facilities: 30 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 1872 (estimated) No. of Female Employees: 336 (estimated)
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36 |
| Safety Phrases | S26 |
| WGK Germany | 1 |
| RTECS | AK5775000 |
| HS Code | 2918300090 |
Customs
| HS Code | 2918300090 |
|---|---|
| Summary | 2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
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Synonyms
| EINECS 203-299-8 |
| Methyl 3-oxobutanoate |
| Butanoic acid, 3-oxo-, methyl ester |
| Methyl acetoacetate |
| 3-Oxobutyric acid methyl ester |
| Acetoacetic Acid Methyl Ester |
| methyl acetoacetate(MAA) |
| MFCD00008784 |
| Methyl 3-Oxobutyrate |
