Introduction：Basic information about CAS 66548-69-4|CL 218872, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | CL 218872 |
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| CAS Number | 66548-69-4 | Molecular Weight | 278.23300 |
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| Density | 1.43g/cm3 | Boiling Point | / |
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| Molecular Formula | C13H9F3N4 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 3-methyl-6-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine |
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| Synonym | More Synonyms |
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CL 218872 BiologicalActivity
| Description | CL 218872 is a selective and orally active benzodiazepine of α1 subunit-containing GABAAreceptor with a Ki of 130 nM. CL 218872 exerts anxiolytic and anticonvulsant in vivo[1]. |
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| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>GABA ReceptorResearch Areas >>Neurological DiseaseSignaling Pathways >>Neuronal Signaling >>GABA Receptor |
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| References | [1]. Squires RF, et al. Some properties of brain specific benzodiazepine receptors: new evidence for multiple receptors. Pharmacol Biochem Behav. 1979 May;10(5):825-30. |
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Chemical & Physical Properties
| Density | 1.43g/cm3 |
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| Molecular Formula | C13H9F3N4 |
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| Molecular Weight | 278.23300 |
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| Exact Mass | 278.07800 |
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| PSA | 43.08000 |
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| LogP | 3.11850 |
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| Index of Refraction | 1.615 |
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| InChIKey | GUOQUXNJZHGPQF-UHFFFAOYSA-N |
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| SMILES | Cc1nnc2ccc(-c3cccc(C(F)(F)F)c3)nn12 |
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| Storage condition | -20°C |
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Synonyms
