CAS 62252-26-0|JLK 6

Introduction：Basic information about CAS 62252-26-0|JLK 6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. JLK 6 BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	JLK 6
CAS Number	62252-26-0	Molecular Weight	225.62800
Density	1.46g/cm3	Boiling Point	456.1ºC at 760 mmHg
Molecular Formula	C₁₀H₈ClNO₃	Melting Point	115 °C
MSDS	/	Flash Point	229.7ºC

Names

Name	7-Amino-4-chloro-3-methoxy-1H-2-benzopyran
Synonym	More Synonyms

JLK 6 BiologicalActivity

Description	JLK-6 markedly reduce the production of amyloid β-peptide (Aβ) by amyloid-β Precursor protein (APP) expressing HEK293 cells by affecting the γ-secretase cleavage of APP, with no effect on the cleavage of the Notch receptor[1].
Related Catalog	Research Areas >>Neurological Disease
References	[1]. Marine Peuchmaur, et al. Further characterization of a putative serine protease contributing to the γ-secretase cleavage of β-amyloid precursor protein. Bioorg Med Chem. 2013 Feb 15;21(4):1018-29.

Chemical & Physical Properties

Density	1.46g/cm3
Boiling Point	456.1ºC at 760 mmHg
Melting Point	115 °C
Molecular Formula	C₁₀H₈ClNO₃
Molecular Weight	225.62800
Flash Point	229.7ºC
Exact Mass	225.01900
PSA	65.46000
LogP	2.61840
Index of Refraction	1.628
InChIKey	AMDGKLWVCUXONP-UHFFFAOYSA-N
SMILES	COc1oc(=O)c2cc(N)ccc2c1Cl

Safety Information

Hazard Codes	Xi
HS Code	2932999099

Customs

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

7-amino-3-methoxy-4-chloroisocoumarin

7-AMINO-4-CHLORO-3-METHOXYISOCOUMARIN

7-Amino-4-chlor-3-methoxyisocumarin

3-methoxy-4-chloro-7-aminoisocoumarin

7-amino-4-chloro-3-methoxy-isochromen-1-one

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