Introduction：Basic information about CAS 1042-42-8|QX 572, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | QX 572 |
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| CAS Number | 1042-42-8 | Molecular Weight | 347.83900 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C18H22ClN3O2 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | bis(2-anilino-2-oxoethyl)-dimethylazanium,chloride |
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| Synonym | More Synonyms |
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QX 572 BiologicalActivity
| Description | Carcainium chloride (QX 572) is a quaternary derivative of the local anesthetic Lidocaine. Antitussive effect[1][2]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| References | [1]. Lavorini F, et al. Antitussive effect of carcainium chloride in patients with chronic cough and idiopathic interstitial pneumonias: A pilot study. Pulm Pharmacol Ther. 2016 Oct;40:91-4. [2]. Adcock JJ, et al. RSD931, a novel anti-tussive agent acting on airway sensory nerves. Br J Pharmacol. 2003 Feb;138(3):407-16. |
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Chemical & Physical Properties
| Molecular Formula | C18H22ClN3O2 |
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| Molecular Weight | 347.83900 |
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| Exact Mass | 347.14000 |
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| PSA | 58.20000 |
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| InChIKey | YGCONRRHHMKQRL-UHFFFAOYSA-N |
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| SMILES | C[N+](C)(CC(=O)Nc1ccccc1)CC(=O)Nc1ccccc1.[Cl-] |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- KH2778000
- CHEMICAL NAME :
- Ethanaminium, N,N-dimethyl-2-oxo-N-(2-oxo-2-(phenylamino)ethyl)-2-( phenylamino)-, chloride
- CAS REGISTRY NUMBER :
- 1042-42-8
- LAST UPDATED :
- 199204
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C18-H22-N3-O2.Cl
- MOLECULAR WEIGHT :
- 347.88
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 94 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 50,212,1987
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Synonyms
| carcainium chloride |
| qx-572 |
