Introduction：Basic information about CAS 120770-34-5|Draflazine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Draflazine |
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| CAS Number | 120770-34-5 | Molecular Weight | 604.51800 |
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| Density | 1.338g/cm3 | Boiling Point | 755.9ºC at 760mmHg |
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| Molecular Formula | C30H33Cl2F2N5O2 | Melting Point | / |
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| MSDS | / | Flash Point | 411ºC |
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Names
| Name | 1-[2-(4-amino-2,6-dichloroanilino)-2-oxoethyl]-4-[5,5-bis(4-fluorophenyl)pentyl]piperazine-2-carboxamide |
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| Synonym | More Synonyms |
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Draflazine BiologicalActivity
| Description | Draflazine (R-75231) is a ENT1 inhibitor. Draflazine (R-75231) completely reverses the hypersensitivity in the complete Freund’s adjuvant (CFA) model of mechanical hyperalgesia and the carrageenan inflammation model of thermal and mechanical hyperalgesia[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| Target | ENT1[1] |
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| References | [1]. Maes SS, et al. Antihyperalgesic activity of nucleoside transport inhibitors in models of inflammatory pain in guinea pigs. J Pain Res. 2012;5:391-400. |
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Chemical & Physical Properties
| Density | 1.338g/cm3 |
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| Boiling Point | 755.9ºC at 760mmHg |
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| Molecular Formula | C30H33Cl2F2N5O2 |
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| Molecular Weight | 604.51800 |
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| Flash Point | 411ºC |
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| Exact Mass | 603.19800 |
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| PSA | 104.69000 |
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| LogP | 6.49650 |
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| Vapour Pressure | 9.69E-23mmHg at 25°C |
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| Index of Refraction | 1.618 |
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| InChIKey | IWMYIWLIESDFRZ-UHFFFAOYSA-N |
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| SMILES | NC(=O)C1CN(CCCCC(c2ccc(F)cc2)c2ccc(F)cc2)CCN1CC(=O)Nc1c(Cl)cc(N)cc1Cl |
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Synonyms
| Draflazine |
| Draflazinum |
| Draflazina |
