Introduction：Basic information about CAS 60875-16-3|4-(3-Methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4-(3-Methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid |
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| CAS Number | 60875-16-3 | Molecular Weight | 218.209 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 477.6±28.0 °C at 760 mmHg |
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| Molecular Formula | C11H10N2O3 | Melting Point | 285 °C (dec.)(lit.) |
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| MSDS | ChineseUSA | Flash Point | 242.7±24.0 °C |
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| Symbol |
GHS07 | Signal Word | Warning |
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Names
| Name | 4-(3-methyl-5-oxo-4H-pyrazol-1-yl)benzoic acid |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | 4-(3-Methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid has hypoglycaemic activity. 4-(3-Methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid follows a mechanism based on the response to the oral glucose overcharge[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease |
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| References | [1]. G M Antón-Fos, et al. Pharmacological Studies of the Two New Hypoglycaemic Compounds 4-(3-methyl-5-oxo-2-pyrazolin-1-yl)benzoic Acid and 1-(mesitylen-2-sulfonyl)-1H-1,2,4-triazole. Arzneimittelforschung. 1994 Jul;44(7):821-6. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 477.6±28.0 °C at 760 mmHg |
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| Melting Point | 285 °C (dec.)(lit.) |
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| Molecular Formula | C11H10N2O3 |
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| Molecular Weight | 218.209 |
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| Flash Point | 242.7±24.0 °C |
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| Exact Mass | 218.069138 |
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| PSA | 69.97000 |
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| LogP | 0.11 |
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| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
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| Index of Refraction | 1.642 |
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| InChIKey | CUGBBQWDGCXWNB-UHFFFAOYSA-N |
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| SMILES | CC1=NN(c2ccc(C(=O)O)cc2)C(=O)C1 |
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Safety Information
| Symbol |
GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H302 |
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| Hazard Codes | Xi: Irritant; |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S24/25 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| HS Code | 2933199090 |
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Customs
| HS Code | 2933199090 |
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| Summary | 2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Articles1
More Articles
| Pharmacological studies of the two new hypoglycaemic compounds 4-(3-methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid and 1-(mesitylen-2-sulfonyl)-1H-1,2,4-triazole. Arzneimittelforschung 44(7) , 821-6, (1994) New compounds showing hypoglycaemic activity have been designed through a computer-aided method based on QSAR (quantitative structure activity relationship) and molecular connectivity. The pharmacolog... | |
Synonyms
| EINECS 262-509-6 |
| Benzoic acid, 4-(4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)- |
| MFCD00003135 |
| 1-(4-Carboxylphenyl)-3-methyl-5-pyrazolone |
| 4-(3-Methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid |
| 4-(3-Methyl-5-oxo-2-pyrazolin-1-yl)benzoicacid |
