Introduction：Basic information about CAS 887650-05-7|Bafetinib, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Bafetinib |
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| CAS Number | 887650-05-7 | Molecular Weight | 576.615 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C30H31F3N8O | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 4-[[(3S)-3-(dimethylamino)pyrrolidin-1-yl]methyl]-N-[4-methyl-3-[(5-pyrimidin-5-ylpyrimidin-2-yl)amino]phenyl]-3-(trifluoromethyl)benzamide |
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| Synonym | More Synonyms |
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Bafetinib BiologicalActivity
| Description | Lyn-IN-1 is a potent and selective dual Bcr-Abl/Lyn inhibitor, extracted from patent WO2014169128A1. |
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| Related Catalog | Signaling Pathways >>Protein Tyrosine Kinase/RTK >>Bcr-AblResearch Areas >>Cancer |
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| References | [1]. From PCT Int.Appl.(2014), WO2014169128A1 |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Molecular Formula | C30H31F3N8O |
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| Molecular Weight | 576.615 |
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| Exact Mass | 576.257263 |
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| PSA | 99.17000 |
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| LogP | 3.03 |
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| Index of Refraction | 1.640 |
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| InChIKey | ZOPBZHLJXQAQON-VWLOTQADSA-N |
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| SMILES | Cc1ccc(NC(=O)c2ccc(CN3CCC(N(C)C)C3)c(C(F)(F)F)c2)cc1Nc1ncc(-c2cncnc2)cn1 |
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Synonyms
| Benzamide, N-[3-([5,5'-bipyrimidin]-2-ylamino)-4-methylphenyl]-4-[[(3S)-3-(dimethylamino)-1-pyrrolidinyl]methyl]-3-(trifluoromethyl)- |
| N-[3-(5,5'-Bipyrimidin-2-ylamino)-4-methylphenyl]-4-{[(3S)-3-(dimethylamino)-1-pyrrolidinyl]methyl}-3-(trifluoromethyl)benzamide |
| QCR-131 |
| cc-271 |
| INNO-406,NS-187,Bafetinib |
| S1369_Selleck |
| Lyn-IN-1 |
