Introduction：Basic information about CAS 171099-57-3|oritavancin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | oritavancin |
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| CAS Number | 171099-57-3 | Molecular Weight | 1793.10000 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C86H97Cl3N10O26 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | oritavancin |
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| Synonym | More Synonyms |
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oritavancin BiologicalActivity
| Description | Oritavancin (LY 333328) is an orally active glycopeptide antibiotic with activity against gram-positive organisms. Oritavancin shows antibacterial effect against multidrug-resistant S. pneumoniae. Oritavancin inhibits cell wall synthesis and disrupts the membrane potential[1][2]. |
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| Related Catalog | Research Areas >>InfectionResearch Areas >>Inflammation/ImmunologySignaling Pathways >>Anti-infection >>Bacterial |
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| References | [1]. Coyle EA, et al. Activity of oritavancin (LY333328), an investigational glycopeptide, compared to that of vancomycin against multidrug-resistant Streptococcus pneumoniae in an in vitro pharmacodynamic model. Antimicrob Agents Chemother. 2001 Mar;45(3):706-9. [2]. Arhin FF, et al. Effect of polysorbate 80 on oritavancin binding to plastic surfaces: implications for susceptibility testing. Antimicrob Agents Chemother. 2008 May;52(5):1597-603. |
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Chemical & Physical Properties
| Molecular Formula | C86H97Cl3N10O26 |
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| Molecular Weight | 1793.10000 |
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| Exact Mass | 1790.56000 |
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| PSA | 560.98000 |
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| LogP | 8.57000 |
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| InChIKey | VHFGEBVPHAGQPI-LXKZPTCJSA-N |
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| SMILES | CNC(CC(C)C)C(=O)NC1C(=O)NC(CC(N)=O)C(=O)NC2C(=O)NC3C(=O)NC(C(=O)NC(C(=O)O)c4cc(O)cc(O)c4-c4cc3ccc4O)C(OC3CC(C)(N)C(O)C(C)O3)c3ccc(c(Cl)c3)Oc3cc2cc(c3OC2OC(CO)C(O)C(O)C2OC2CC(C)(NCc3ccc(-c4ccc(Cl)cc4)cc3)C(O)C(C)O2)Oc2ccc(cc2Cl)C1O |
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Safety Information
Synonyms
