CAS 104809-32-7|β-Nicotinamide adenine dinucleotide reduced dipotassium
| Common Name | β-Nicotinamide adenine dinucleotide reduced dipotassium | ||
|---|---|---|---|
| CAS Number | 104809-32-7 | Molecular Weight | 741.62200 |
| Density | / | Boiling Point | / |
| Molecular Formula | C21H27K2N7O14P2 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | / |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | [[5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate,potassium |
|---|---|
| Synonym | More Synonyms |
BiologicalActivity
| Description | β-Nicotinamide adenine dinucleotide reduced dipotassium is an orally active reduced coenzyme. β-Nicotinamide adenine dinucleotide reduced dipotassium is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. β-Nicotinamide adenine dinucleotide reduced dipotassium plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle[1]. |
|---|---|
| Related Catalog | Research Areas >>Metabolic Disease |
| References | [1]. Ying W. NAD+ and NADH in cellular functions and cell death. Front Biosci. 2006 Sep 1;11:3129-48. |
Chemical & Physical Properties
| Molecular Formula | C21H27K2N7O14P2 |
|---|---|
| Molecular Weight | 741.62200 |
| Exact Mass | 741.03700 |
| PSA | 342.90000 |
| InChIKey | ZUPXXZAVUHFCNV-UHFFFAOYSA-N |
| SMILES | NC(=O)C1=CN(C2OC(COP(=O)(O)OP(=O)(O)OCC3OC(n4cnc5c(N)ncnc54)C(O)C3O)C(O)C2O)C=CC1.[K] |
| Storage condition | 20°C |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26-36 |
| RIDADR | NONH for all modes of transport |
Articles7
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| ADP-ribosylation of histones by ARTD1: An additional module of the histone code? FEBS Lett. 585 , 1595-1599, (2011) ADP-ribosylation is a covalent post-translational protein modification catalyzed by ADP-ribosyltransferases and is involved in important processes such as cell cycle regulation, DNA damage response, r... | |
| Mammalian sirtuins and energy metabolism. Int. J. Biol. Sci. 7 , 575-587, (2011) Sirtuins are highly conserved NAD+-dependent protein deacetylases and/or ADP-ribosyltransferases that can extend the lifespan of several lower model organisms including yeast, worms and flies. The sev... |
Synonyms
| |A-Nicotinamide adenine dinucleotide,reduced dipotassium salt |
| Diphosphopyridine nucleotide,reduced form |
