CAS 327-78-6|4-Chloro-3-(trifluoromethyl)phenylisocyanate
Introduction：Basic information about CAS 327-78-6|4-Chloro-3-(trifluoromethyl)phenylisocyanate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4-Chloro-3-(trifluoromethyl)phenylisocyanate | ||
|---|---|---|---|
| CAS Number | 327-78-6 | Molecular Weight | 221.564 |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 201.7±0.0 °C at 760 mmHg |
| Molecular Formula | C8H3ClF3NO | Melting Point | 40-42 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 99.4±0.0 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 4-Chloro-3-(trifluoromethyl)phenyl isocyanate |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 201.7±0.0 °C at 760 mmHg |
| Melting Point | 40-42 °C(lit.) |
| Molecular Formula | C8H3ClF3NO |
| Molecular Weight | 221.564 |
| Flash Point | 99.4±0.0 °C |
| Exact Mass | 220.985519 |
| PSA | 29.43000 |
| LogP | 4.93 |
| Vapour Pressure | 0.3±0.3 mmHg at 25°C |
| Index of Refraction | 1.487 |
| InChIKey | NBJZEUQTGLSUOB-UHFFFAOYSA-N |
| SMILES | O=C=Nc1ccc(Cl)c(C(F)(F)F)c1 |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H312-H315-H319-H332-H335 |
| Precautionary Statements | P261-P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R20/21/22;R36/37/38 |
| Safety Phrases | S7-S26-S27-S37/39-S36/37/39-S45-S23 |
| RIDADR | UN 2206 6.1/PG 3 |
| WGK Germany | 3 |
| Packaging Group | III |
| Hazard Class | 6.1 |
| HS Code | 2929109000 |
Customs
| HS Code | 2929109000 |
|---|---|
| Summary | 2929109000. other isocyanates. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Articles5
More Articles| Synthesis and inhibitory activity of thymidine analogues targeting Mycobacterium tuberculosis thymidine monophosphate kinase Bioorg. Med. Chem. 19(24) , 7603-1, (2011) We report on Mycobacterium tuberculosis thymidine monophosphate kinase (TMPKmt) inhibitory activities of a series of new 3'- and 5'-modified thymidine analogues including α- and β-derivatives. In addi... | |
| Synthesis and biological evaluation of sorafenib- and regorafenib-like sEH inhibitors. Bioorg. Med. Chem. Lett. 23(13) , 3732-7, (2013) To reduce the pro-angiogenic effects of sEH inhibition, a structure-activity relationship (SAR) study was performed by incorporating structural features of the anti-angiogenic multi-kinase inhibitor s... | |
| A novel p21 attenuator which is structurally related to sorafenib. Cancer Biol. Ther. 14(3) , 278-85, (2013) p21 is a member of the cyclin kinase inhibitor family of proteins and plays pivotal roles in cellular proliferation as well as in the regulation of apoptosis, and thus has diverse functions in disease... |
Synonyms
| Sorafenib intermediate 3 |
| Isocyanic Acid 4-Chloro-3-(trifluoromethyl)phenyl Ester |
| 1-chloro-4-isocyanato-2-trifluoromethylbenzene |
| 3-TRIFLUOROMETHYL-4-CHLORO-PHENYL ISOCYANATE |
| 4-Cl-3CF3-phenyl isocyanate |
| 4-Chloro-3-(trifluoromethyl)phenyl isocyanate |
| MFCD00013874 |
| 1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene |
| 4-Chloro-3-(trifluoromethyl)phenylisocyanate |
| Benzene, 1-chloro-4-isocyanato-2-(trifluoromethyl)- |
