CAS 5725-89-3|Resorufin methyl ether
| Common Name | Resorufin methyl ether | ||
|---|---|---|---|
| CAS Number | 5725-89-3 | Molecular Weight | 227.21500 |
| Density | 1.33 g/cm3 | Boiling Point | 378.8ºC at 760 mmHg |
| Molecular Formula | C13H9NO3 | Melting Point | ≥220ºC(lit.) |
| MSDS | ChineseUSA | Flash Point | 187.3ºC |
Names
| Name | Resorufin methyl ether |
|---|---|
| Synonym | More Synonyms |
Resorufin methyl ether BiologicalActivity
| Description | Resorufin methyl ether (Methoxyresorufin) is a cytochrome P450 fluorometric substrate[1]. Resorufin methyl ether is a relatively specific substrate for CYP1A2 activity in rodents[1][2]. |
|---|---|
| Related Catalog | Signaling Pathways >>Metabolic Enzyme/Protease >>Cytochrome P450Research Areas >>Others |
| References | [1]. P V Nerurkar, et al. Methoxyresorufin and benzyloxyresorufin: substrates preferentially metabolized by cytochromes P4501A2 and 2B, respectively, in the rat and mouse. Biochem Pharmacol. 1993 Sep 1;46(5):933-43. [2]. Hansen Murcia, et al. Study on the inhibitory effect of furafylline and troleandomycin in the 7-methoxyresorufin-O-demethylase and nifedipine oxidase activities in hepatic microsomes from four poultry species using high-performance liquid chromatography coupled with fluorescence and ultraviolet detection. J Pharm Biomed Anal. 2019 Feb 5;164:148-154. |
Chemical & Physical Properties
| Density | 1.33 g/cm3 |
|---|---|
| Boiling Point | 378.8ºC at 760 mmHg |
| Melting Point | ≥220ºC(lit.) |
| Molecular Formula | C13H9NO3 |
| Molecular Weight | 227.21500 |
| Flash Point | 187.3ºC |
| Exact Mass | 227.05800 |
| PSA | 52.33000 |
| LogP | 2.30140 |
| Index of Refraction | 1.638 |
| InChIKey | KNYYMGDYROYBRE-UHFFFAOYSA-N |
| SMILES | COc1ccc2nc3ccc(=O)cc-3oc2c1 |
| Storage condition | 2-8°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2934999090 |
Customs
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles26
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| Sex-specific differences in hyperoxic lung injury in mice: role of cytochrome P450 (CYP)1A. Toxicology 331 , 14-23, (2015) Sex-specific differences in pulmonary morbidity in adults and preterm infants are well documented. Hyperoxia contributes to lung injury in experimental animals and humans. Cytochrome P450 (CYP) 1A enz... | |
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Synonyms
| 7-methoxyphenoxazin-3-one |
| MFCD00037663 |
