Introduction：Basic information about CAS 3223-07-2|Melphalan hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Melphalan hydrochloride |
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| CAS Number | 3223-07-2 | Molecular Weight | 341.661 |
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| Density | / | Boiling Point | 473.1ºC at 760mmHg |
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| Molecular Formula | C13H19Cl3N2O2 | Melting Point | / |
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| MSDS | / | Flash Point | 239.9ºC |
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Names
| Name | Melphalan hydrochloride |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Boiling Point | 473.1ºC at 760mmHg |
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| Molecular Formula | C13H19Cl3N2O2 |
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| Molecular Weight | 341.661 |
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| Flash Point | 239.9ºC |
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| Exact Mass | 340.051208 |
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| PSA | 66.56000 |
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| LogP | 3.42730 |
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| InChIKey | OUUYBRCCFUEMLH-YDALLXLXSA-N |
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| SMILES | Cl.NC(Cc1ccc(N(CCCl)CCCl)cc1)C(=O)O |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- AY4025000
- CHEMICAL NAME :
- Alanine, 3-(p-(bis(2-chloroethyl)amino)phenyl)-, monohydrochloride, L-
- CAS REGISTRY NUMBER :
- 3223-07-2
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C13-H18-Cl2-N2-O2.Cl-H
- MOLECULAR WEIGHT :
- 341.69
- WISWESSER LINE NOTATION :
- QVYZ1R DN2G2G &GH -L
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 1200 ug/kg/5D-I
- TOXIC EFFECTS :
- Gastrointestinal - nausea or vomiting
- REFERENCE :
- CCROBU Cancer Chemotherapy Reports, Part 1. (Washington, DC) V.52(6)-59, 1968-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 57,369,1973
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 430 ug/kg
- TOXIC EFFECTS :
- Blood - leukopenia Blood - thrombocytopenia Blood - other changes
- REFERENCE :
- CCSUBJ Cancer Chemotherapy Reports, Part 2. (Washington, DC) V.1-5, 1964-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 2,201,1965
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 430 ug/kg
- TOXIC EFFECTS :
- Blood - leukopenia Blood - agranulocytosis Blood - other changes
- REFERENCE :
- CCSUBJ Cancer Chemotherapy Reports, Part 2. (Washington, DC) V.1-5, 1964-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 2,201,1965 ** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1300 ug/kg/4W
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors
- REFERENCE :
- JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 36,915,1966
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Safety Information
| Hazard Codes | Xn |
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| HS Code | 2922499990 |
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Customs
| HS Code | 2922499990 |
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| Summary | HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0% |
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Synonyms
| DL-Alanine, 3-(p-(bis(2-chloroethyl)amino)phenyl)-, hydrochloride |
| DL-Alanine, 3-(p-(bis(2-chloroethyl)amino)phenyl)-, monohydrochloride |
| L-phenylalanine, 4-[bis(2-chloroethyl)amino]-, monohydrochloride |
| 4-[Bis(2-chloroethyl)amino]-L-phenylalanine hydrochloride (1:1) |
| acide (2S)-2-amino-3-{4-[bis(2-chloroéthyl)amino]phényl}propanoïque chlorhydrate |
| DL-Phenylalanine, 4-(bis(2-chloroethyl)amino)-, monohydrochloride (9CI) |
| L-Phenylalanine, 4-(bis(2-chloroethyl)amino)-, monohydrochloride (9CI) |
| (2S)-2-amino-3-{4-[bis(2-chloroethyl)amino]phenyl}propanoic acid hydrochloride |
| 4-(Bis(2-chloroethyl)amino)-L-phenylalanine Monohydrochloride |
| 3-(p-(Bis(β-chloroethyl)amino)phenyl)-D,L-alanine hydrochloride |
| 4-(Bis(2-chloroethyl)amino)-DL-phenylalanine hydrochloride |
| Melphalan Hydrochloride,Phenylalanine, 4-[bis(2-chloroethyl)amino]-, hydrochloride (1:1) |
| (2S)-2-Amino-3-{4-[bis(2-chlorethyl)amino]phenyl}propansäurehydrochlorid |
| 3-[p-[Bis(β-chloroethyl)amino]phenyl]-D,L-alanine, hydrochloride |
| 4-[bis(2-chloroethyl)amino]-L-phenylalanine hydrochloride |
| L-Phenylalanine, 4-[bis(2-chloroethyl)amino]-, hydrochloride (1:1) |
| 3-(p-(Bis(2-chloroethyl)amino)phenyl)-DL-alanine hydrochloride |
| DL-Alanine, 3-(p-[bis(2-chloroethyl)amino]phenyl)-, hydrochloride |
| L-Alanine, 3-(p-[bis(2-chloroethyl)amino]phenyl)-, hydrochloride |
| 3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine Hydrochloride |
