CAS 6027-13-0|DL-Homocysteine
| Common Name | DL-Homocysteine | ||
|---|---|---|---|
| CAS Number | 6027-13-0 | Molecular Weight | 135.185 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 299.7±35.0 °C at 760 mmHg |
| Molecular Formula | C4H9NO2S | Melting Point | 231 °C |
| MSDS | ChineseUSA | Flash Point | 135.0±25.9 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | L-homocysteine |
|---|---|
| Synonym | More Synonyms |
DL-Homocysteine BiologicalActivity
| Description | L-Homocysteine, a homocysteine metabolite, is a homocysteine that has L configuration. L-Homocysteine induces upregulation of cathepsin V that mediates vascular endothelial inflammation in hyperhomocysteinaemia[1][2]. |
|---|---|
| Related Catalog | Research Areas >>Inflammation/Immunology |
| Target | Human Endogenous Metabolite |
| References | [1]. Finkelstein JD, et al. Homocysteine. Int J Biochem Cell Biol. 2000 Apr;32(4):385-9. [2]. Leng YP, et al. l-Homocysteine-induced cathepsin V mediates the vascular endothelial inflammation in hyperhomocysteinaemia. Br J Pharmacol. 2018 Apr;175(8):1157-1172. |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 299.7±35.0 °C at 760 mmHg |
| Melting Point | 231 °C |
| Molecular Formula | C4H9NO2S |
| Molecular Weight | 135.185 |
| Flash Point | 135.0±25.9 °C |
| Exact Mass | 135.035400 |
| PSA | 102.12000 |
| LogP | 0.22 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.538 |
| InChIKey | FFFHZYDWPBMWHY-VKHMYHEASA-N |
| SMILES | NC(CCS)C(=O)O |
| Storage condition | ?20°C |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Hazard Codes | Xn |
| Risk Phrases | 22 |
| RIDADR | NONH for all modes of transport |
Articles86
More Articles| Biomarkers of one-carbon metabolism are associated with biomarkers of inflammation in women. J. Nutr. 144(5) , 714-21, (2014) Folate-mediated one-carbon metabolism is essential for DNA synthesis, repair, and methylation. Perturbations in one-carbon metabolism have been implicated in increased risk of some cancers and may als... | |
| Abstracts of the 9th International Conference On Homocysteine and One-Carbon Metabolism - HCY2013. Dublin, Ireland. September 8-12, 2013. J. Inherit. Metab. Dis. 36 Suppl 1 , S1-54, (2013) | |
| Derivation and validation of homocysteine score in u.s. Men and women. J. Nutr. 145(1) , 96-104, (2015) One-carbon metabolism, which is crucial in DNA synthesis and genomic stability, is an interrelated network of biochemical reactions involved in several dietary and lifestyle factors. The development o... |
Synonyms
| (2S)-2-amino-4-sulfanylbutanoic acid |
| Homocysteine, L- |
| L-2-Amino-4-Mercapto-butyric acid |
| (S)-2-amino-4-mercapto-Butanoic acid |
| DL-2-amino-4-mercapto-Butyric acid |
| HOMO-CYS |
| H-Hcys-OH |
| Butyric acid, 2-amino-4-mercapto- |
| DL-2-Amino-4-mercaptobutyric acid |
| Butyric acid, 2-amino-4-mercapto-, DL- |
| (S)-2-Amino-4-mercaptobutanoic acid |
| 2-Amino-4-mercaptobutyric acid |
| D,L-Homocysteine |
| Butanoic acid, 2-amino-4-mercapto-, (S)- |
| (S)-homocysteine |
| MFCD00151320 |
| Butanoic acid, 2-amino-4-mercapto- |
| 2-amino-4-mercapto-DL-Butyric acid |
| 2-amino-4-sulfanylbutanoic acid |
| EINECS 227-891-0 |
| D,L-homocystine |
| Homocysteine (VAN) |
| 2-Amino-4-Mercapto-Butyric Acid |
| (S)-2-Amino-4-mercaptobutyric acid |
| (±)-Homocysteine |
| 2-amino-4-mercapto-Butanoic acid |
| UNII:S7IJP4A89K |
| Homocysteine |
| Butyric acid, 2-amino-4-mercapto-, DL- (9CI) |
