Introduction：Basic information about CAS 466-09-1|Odorigenin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Odorigenin |
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| CAS Number | 466-09-1 | Molecular Weight | 374.514 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 549.3±50.0 °C at 760 mmHg |
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| Molecular Formula | C23H34O4 | Melting Point | 240-256° |
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| MSDS | / | Flash Point | 188.2±23.6 °C |
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Names
| Name | 3β,14-dihydroxy-5α,14β-card-20(22)-enolide |
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| Synonym | More Synonyms |
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Odorigenin BiologicalActivity
| Description | Uzarigenin (NSC 119993; NSC 277290; Odorigeni) is a carnolide can be isolated from Pergularia tomentosa and exhibits antiproliferative activity. Uzarigenin resists the proliferation of PC3 cells, HeLa cells, Calu-1 cells, MCF-7 cells and U251MG cells, with IC50 values of 0.3 μM, 3.0 μM, 8.0 μM, 6.0 μM and 6.0 μM respectively[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
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| References | [1]. Hosseini SH, et al. Antiproliferative Cardenolides from the Aerial Parts of Pergularia tomentosa. J Nat Prod. 2019 Jan 25;82(1):74-79. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 549.3±50.0 °C at 760 mmHg |
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| Melting Point | 240-256° |
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| Molecular Formula | C23H34O4 |
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| Molecular Weight | 374.514 |
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| Flash Point | 188.2±23.6 °C |
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| Exact Mass | 374.245697 |
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| PSA | 66.76000 |
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| LogP | 2.79 |
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| Vapour Pressure | 0.0±3.4 mmHg at 25°C |
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| Index of Refraction | 1.591 |
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| InChIKey | XZTUSOXSLKTKJQ-UHFFFAOYSA-N |
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| SMILES | CC12CCC(O)CC1CCC1C2CCC2(C)C(C3=CC(=O)OC3)CCC12O |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- YV1950000
- CHEMICAL NAME :
- Uzarigenin
- CAS REGISTRY NUMBER :
- 466-09-1
- BEILSTEIN REFERENCE NO. :
- 0095446
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C23-H34-O4
- MOLECULAR WEIGHT :
- 374.57
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 1379 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 13,1029,1970 *** REVIEWS *** TOXICOLOGY REVIEW 85ELDJ "Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963 Volume(issue)/page/year: -,194,1963
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Safety Information
Synonyms
| Odorigenin |
| 5α-Card-20(22)-enolide, 3β,14-dihydroxy- |
| 3b,14-Dihydroxy-5a-card-20(22)-enolide |
| UZARIGENIN |
| ODORIGENIN B |
| Card-20(22)-enolide, 3,14-dihydroxy-, (3β,5α)- |
| (3β,5α)-3,14-Dihydroxycard-20(22)-enolide |
| uzarigenine |
