Introduction：Basic information about CAS 483-10-3|Yohimban-16-carboxylicacid, 17-hydroxy-, methyl ester, (16b,17a)-, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Yohimban-16-carboxylicacid, 17-hydroxy-, methyl ester, (16b,17a)- |
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| CAS Number | 483-10-3 | Molecular Weight | 354.44 |
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| Density | 1.31g/cm3 | Boiling Point | 543ºC at 760mmHg |
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| Molecular Formula | C21H26N2O3 | Melting Point | 225-230ºC |
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| MSDS | / | Flash Point | / |
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Names
| Name | Corynanthine |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | Corynanthine is a selective α1-adrenergic receptor antagonist. Corynanthine can significantly lower intraocular pressure in rabbits[1]. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>Adrenergic ReceptorResearch Areas >>Neurological Disease |
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| References | [1]. Serle JB, et, al. Corynanthine and aqueous humor dynamics in rabbits and monkeys. Arch Ophthalmol. 1984 Sep;102(9):1385-8. |
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Chemical & Physical Properties
| Density | 1.31g/cm3 |
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| Boiling Point | 543ºC at 760mmHg |
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| Melting Point | 225-230ºC |
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| Molecular Formula | C21H26N2O3 |
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| Molecular Weight | 354.44 |
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| Exact Mass | 354.19400 |
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| PSA | 65.56000 |
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| LogP | 2.58500 |
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| Vapour Pressure | 1.27E-12mmHg at 25°C |
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| Index of Refraction | 1.66 |
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| InChIKey | BLGXFZZNTVWLAY-DKJBZYCGSA-N |
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| SMILES | COC(=O)C1C(O)CCC2CN3CCc4c([nH]c5ccccc45)C3CC21 |
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Safety Information
| Risk Phrases | 25 |
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| Safety Phrases | 1-20-45 |
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| RIDADR | UN 1544 |
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| WGK Germany | 3 |
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Synonyms
| RAUHIMBINE |
| Rauhimbin |
| Corynanthin |
| corynanthine free base |
| corynantine |
| rauwolscine |
| Coynanthine |
| CORYNANTHINE DIHYDRATE |
