CAS 1035-77-4|Estra-1,3,5(10)-trien-17-ol,3-methoxy-, (17b)-

Introduction：Basic information about CAS 1035-77-4|Estra-1,3,5(10)-trien-17-ol,3-methoxy-, (17b)-, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Synonyms

Common Name	Estra-1,3,5(10)-trien-17-ol,3-methoxy-, (17b)-
CAS Number	1035-77-4	Molecular Weight	286.40900
Density	1.109 g/cm3	Boiling Point	428.8ºC at 760 mmHg
Molecular Formula	C₁₉H₂₆O₂	Melting Point	/
MSDS	/	Flash Point	187.9ºC

Names

Name	(8R,9S,13S,14S,17S)-3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-ol
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.109 g/cm3
Boiling Point	428.8ºC at 760 mmHg
Molecular Formula	C₁₉H₂₆O₂
Molecular Weight	286.40900
Flash Point	187.9ºC
Exact Mass	286.19300
PSA	29.46000
LogP	3.91220
Vapour Pressure	4.07E-08mmHg at 25°C
Index of Refraction	1.566
InChIKey	ULAADVBNYHGIBP-GFEQUFNTSA-N
SMILES	COc1ccc2c(c1)CCC1C2CCC2(C)C(O)CCC12

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KG7732000

CHEMICAL NAME :: Estra-1,3,5(10)-trien-17-beta-ol, 3-methoxy-

CAS REGISTRY NUMBER :: 1035-77-4

LAST UPDATED :: 198910

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C19-H26-O2

MOLECULAR WEIGHT :: 286.45

WISWESSER LINE NOTATION :: L E5 B666TTT&J E1 FQ OO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 2 mg/kg

SEX/DURATION :: male 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands

REFERENCE :: ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 49,193,1965

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 2500 ug/kg

SEX/DURATION :: female 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Fertility - other measures of fertility

REFERENCE :: ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 49,193,1965

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 132 ug/kg

SEX/DURATION :: female 3 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - other measures of fertility

REFERENCE :: ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 47,444,1964

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 1050 ug/kg

SEX/DURATION :: female 3-9 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)

REFERENCE :: ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 47,444,1964

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 3 mg/kg

SEX/DURATION :: female 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - other measures of fertility

REFERENCE :: 85GRAA "The Control of Fertility," Pincus, G., New York, Academic Press, 1965 Volume(issue)/page/year: -,57,1965

Synonyms

3-methoxyestra-1,3,5(10)-trien-17-|A-ol

EINECS 213-858-8

17beta-Estradiol 3-methyl ether

[3H]-3-Methoxyestradiol

Oestradiol 3-methyl ether

[14C]-3-Methoxyestradiol

3-Methoxyoestradiol

3-O-Methyl Estradiol

Estradiol 3-methyl ether

3-Methoxyestradiol

Estradiol-17beta-3-methyl ether

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