Introduction：Basic information about CAS 32434-44-9|Isofebrifugine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Isofebrifugine |
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| CAS Number | 32434-44-9 | Molecular Weight | 301.34000 |
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| Density | 1.48±0.1 g/cm3 (20 ºC 760 Torr) | Boiling Point | 519.8±58.0 °C(Predicted) |
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| Molecular Formula | C16H19N3O3 | Melting Point | 138-139 ºC |
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| MSDS | / | Flash Point | / |
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Names
| Name | (+)-isofebrifugine |
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| Synonym | More Synonyms |
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Isofebrifugine BiologicalActivity
| Description | Isofebrifugine, isolated from a Chinese medicinal plant, Chang Shan (Dichroa febrifuga), is a natural quinazolinone alkaloid with important physiological activities and good pharmacological effects. Antimalarial effect[1]. |
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| Related Catalog | Research Areas >>Infection |
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| References | [1]. Kobayashi S, et al. Catalytic Asymmetric Synthesis of Antimalarial Alkaloids Febrifugine and Isofebrifugine and Their Biological Activity.J Org Chem. 1999 Sep 3;64(18):6833-6841. |
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Chemical & Physical Properties
| Density | 1.48±0.1 g/cm3 (20 ºC 760 Torr) |
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| Boiling Point | 519.8±58.0 °C(Predicted) |
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| Melting Point | 138-139 ºC |
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| Molecular Formula | C16H19N3O3 |
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| Molecular Weight | 301.34000 |
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| Exact Mass | 301.14300 |
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| PSA | 76.38000 |
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| LogP | 0.95480 |
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| InChIKey | YLYLCQRQSRDSQR-ADTLFGHVSA-N |
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| SMILES | O=c1c2ccccc2ncn1CC1(O)CC2NCCCC2O1 |
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| Water Solubility | Very slightly soluble (0.28 g/L) (25 ºC) |
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Synonyms
| (+)-inthomycin A |
| Phthoxazolin A |
| 4,6,8-Decatrienamide,3-hydroxy-2,2,4-trimethyl-10-(5-oxazolyl)-,(R-(Z,Z,E)) |
| Phthoxazolin |
| (R-(Z,Z,E))-3-Hydroxy-2,2,4-trimethyl-10-(5-oxazolyl)-4,6,8-decatrienamide |
