CAS 14173-39-8|Fenclonine
| Common Name | Fenclonine | ||
|---|---|---|---|
| CAS Number | 14173-39-8 | Molecular Weight | 199.634 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 339.5±32.0 °C at 760 mmHg |
| Molecular Formula | C9H10ClNO2 | Melting Point | 235-238ºC |
| MSDS | ChineseUSA | Flash Point | 159.1±25.1 °C |
| Symbol | GHS06 | Signal Word | Danger |
Names
| Name | 4-Chloro-Phe-OH |
|---|---|
| Synonym | More Synonyms |
Fenclonine BiologicalActivity
| Description | 4-Chloro-L-phenylalanine (L-PCPA) is a 5-HT biosynthesis inhibitor. 4-Chloro-L-phenylalanine is also a nonspecific antagonist of both isoforms of tryptophan hydroxylase (TPH1 and TPH2)[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Metabolic Enzyme/Protease >>Tryptophan HydroxylaseResearch Areas >>Neurological DiseaseSignaling Pathways >>GPCR/G Protein >>5-HT ReceptorSignaling Pathways >>Neuronal Signaling >>5-HT Receptor |
| References | [1]. Chasen J Greig, et al. Enhanced serotonin signaling increases intestinal neuroplasticity. J Surg Res. 2016 Nov;206(1):151-158. |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 339.5±32.0 °C at 760 mmHg |
| Melting Point | 235-238ºC |
| Molecular Formula | C9H10ClNO2 |
| Molecular Weight | 199.634 |
| Flash Point | 159.1±25.1 °C |
| Exact Mass | 199.040009 |
| PSA | 63.32000 |
| LogP | 1.71 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.590 |
| InChIKey | NIGWMJHCCYYCSF-QMMMGPOBSA-N |
| SMILES | NC(Cc1ccc(Cl)cc1)C(=O)O |
Safety Information
| Symbol | GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301-H317 |
| Precautionary Statements | P280-P301 + P310 |
| Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
| Hazard Codes | T:Toxic; |
| Risk Phrases | R25;R43 |
| Safety Phrases | S36/37-S45 |
| RIDADR | UN 2811 |
| WGK Germany | 3 |
| Hazard Class | 6.1 |
| HS Code | 2922499990 |
Customs
| HS Code | 2922499990 |
|---|---|
| Summary | HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0% |
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Synonyms
| Dl-4-Chlorophenylalanine |
| L-4-Chlorophenylalanine |
| para-Chlorophenylalanine |
| PCPA |
| (±)-p-Chlorophenylalanine |
| (S)-2-Amino-3-(4-chlorophenyl)propanoic acid |
| p-Cl-L-Phe-OH |
| p-Chloro-L-phenylalanine |
| p-Chloro-DL-phenylalanine |
| 4-Chlorophenylalanine |
| 4-Chloro-phenylalanine |
| Phenylalanine, 4-chloro- |
| 4-Chloro-3-phenylalanine |
| DL-p-Chlorophenylalanine |
| 4-Chloro-DL-phenylalanine |
| p-Chlorophenylalanine |
| 4-Chloro-L-phenylalanine |
| MFCD00063065 |
| p-CPA |
| 3-(p-chlorophenyl)-DL-alanine |
| Fenclonine |
| (2S)-2-amino-3-(4-chlorophenyl)propanoic acid |
| DL-3-(p-Chlorophenyl)alanine |
| EINECS 238-023-5 |
| (S)-4-Chlorophenylalanine |
| (±)-p-Chlorphenylalanine |
| L-p-Chlorophenylalanine |
| 4-Chloro-dl-β-phenylalanine |
