CAS 566-26-7|cholest-5-en-3β,7α-diol

Introduction:Basic information about CAS 566-26-7|cholest-5-en-3β,7α-diol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Namecholest-5-en-3β,7α-diol
CAS Number566-26-7Molecular Weight402.65300
Density1.03g/cm3Boiling Point515.3ºC at 760mmHg
Molecular FormulaC27H46O2Melting Point168-170ºC
MSDS/Flash Point214.7ºC

Names

Name7α-hydroxycholesterol
SynonymMore Synonyms

cholest-5-en-3β,7α-diol BiologicalActivity

Description7α-Hydroxycholesterol is a cholesterol oxide and is formed by both enzymatic and non-enzymatic oxidation. 7α-Hydroxycholesterol can be used as a biomarker for lipid peroxidation[1][2].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
References

[1]. Ferderbar S, et al. Cholesterol oxides as biomarkers of oxidative stress in type 1 and type 2 diabetes mellitus. Diabetes Metab Res Rev. 2007 Jan;23(1):35-42.

[2]. Kitano S, et al. Oxidative status of human low density lipoprotein isolated by anion-exchange high-performance liquid chromatography--assessment by total hydroxyoctadecadienoic acid, 7-hydroxycholesterol, and 8-iso-prostaglandin F(2alpha). Anal Chim Acta. 2007 Feb 28;585(1):86-93.

Chemical & Physical Properties

Density1.03g/cm3
Boiling Point515.3ºC at 760mmHg
Melting Point168-170ºC
Molecular FormulaC27H46O2
Molecular Weight402.65300
Flash Point214.7ºC
Exact Mass402.35000
PSA40.46000
LogP6.35950
Index of Refraction1.536
InChIKeyOYXZMSRRJOYLLO-RVOWOUOISA-N
SMILESCC(C)CCCC(C)C1CCC2C3C(O)C=C4CC(O)CCC4(C)C3CCC12C
Storage condition-20°C

Synonyms

7|A-hydroxycholesterol
7Alpha-Hydroxy Cholesterol
Cholest-5-en-3beta,7alpha-diol
Cholest-5-ene-3beta,7alpha-diol
(3S,7S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
7alpha-hydroxycholesterol
7alpha-Cholesterol
CAS 56618-58-7|Methyl 3-Hydroxydecanoate
CAS 566-28-9|7-KETOCHOLESTEROL
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