Introduction：Basic information about CAS 100750-39-8|N-Acetyl-3-acetoxy-5-phenylpyrrole, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | N-Acetyl-3-acetoxy-5-phenylpyrrole |
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| CAS Number | 100750-39-8 | Molecular Weight | 243.25800 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C14H13NO3 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | (1-acetyl-5-phenylpyrrol-3-yl) acetate |
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| Synonym | More Synonyms |
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N-Acetyl-3-acetoxy-5-phenylpyrrole BiologicalActivity
| Description | APPA is an aldose reductase inhibitor. APPA can effectively prevent apoptosis and the symptoms of Streptozotocin (HY-13753)-induced diabetes by inhibiting the polyol pathway in rats. APPA has the potential for diabetic nephropathy (DN) research[1]. |
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| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisSignaling Pathways >>Metabolic Enzyme/Protease >>Aldose ReductaseResearch Areas >>Metabolic Disease |
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| References | [1]. Zhi-Ming Xiu, et al. 1-Acetyl-5-phenyl-1H-pyrrol-3-ylacetate: An aldose reductase inhibitor for the treatment of diabetic nephropathy. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4482-4487. |
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Chemical & Physical Properties
| Molecular Formula | C14H13NO3 |
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| Molecular Weight | 243.25800 |
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| Exact Mass | 243.09000 |
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| PSA | 48.30000 |
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| LogP | 2.74050 |
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| InChIKey | WKSITCBIIIHVSF-UHFFFAOYSA-N |
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| SMILES | CC(=O)Oc1cc(-c2ccccc2)n(C(C)=O)c1 |
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Synonyms
| N-ACETYL-3-ACETOXY-5-PHENYLPYRROLE |
| 1-Acetyl-5-phenyl-1H-pyrrol-3-ol Acetate |
| 4-acetoxy-1-acetyl-2-phenyl-pyrrole |
