CAS 102013-72-9|m-PEG8-CH2COOH

Introduction:Basic information about CAS 102013-72-9|m-PEG8-CH2COOH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Namem-PEG8-CH2COOH
CAS Number102013-72-9Molecular Weight442.49800
Density1.122Boiling Point/
Molecular FormulaC19H38O11Melting Point/
MSDS/Flash Point/

Names

Name2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
SynonymMore Synonyms

m-PEG8-CH2COOH BiologicalActivity

Descriptionm-PEG8-CH2COOH is a PEG--based PROTAC linker can be used in the synthesis of PROTACs.
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Alexander Chucholowski, et al. Cyclodextrin conjugates. WO2010017328A2.

Chemical & Physical Properties

Density1.122
Molecular FormulaC19H38O11
Molecular Weight442.49800
Exact Mass442.24100
PSA120.37000
InChIKeyAOKQPSPNBHUGLR-UHFFFAOYSA-N
SMILESCOCCOCCOCCOCCOCCOCCOCCOCCOCC(=O)O

Safety Information

Hazard CodesXi

Synonyms

3,6,9,12,15,18,21,24,27-nonaoxa-octacosanoic acid
3,6,9,12,15,18,21,24,27-Nonaoxa-octacosansaeure
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