CAS 109276-34-8|Biotin LC hydrazide
| Common Name | Biotin LC hydrazide | ||
|---|---|---|---|
| CAS Number | 109276-34-8 | Molecular Weight | 371.49800 |
| Density | 1.188 g/cm3 | Boiling Point | 777ºC at 760 mmHg |
| Molecular Formula | C16H29N5O3S | Melting Point | 195-196°C |
| MSDS | ChineseUSA | Flash Point | 423.7ºC |
Names
| Name | (+)-Biotinamidohexanoic acid hydrazide |
|---|---|
| Synonym | More Synonyms |
Biotin LC hydrazide BiologicalActivity
| Description | Biotin LC hydrazide is a long chain protein modification reagent, which can transform periodate-oxidized glycoproteins. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersBiochemical Assay ReagentsResearch Areas >>Others |
| In Vitro | Biotin LC hydrazide (BACH) is often used to target glycoproteins and glycans. It is carbohydrate reactive and is more sensitive than biotin hydrazide[1]. A new biotinylating system for DNA using Biotin LC hydrazide (biotin aminocaproyl hydrazide) and glutaraldehyde[2]. |
| References | [1]. O'Shannessy DJ, et al. Quantitation of glycoproteins on electroblots using the biotin-streptavidin complex. Anal Biochem. 1987 May 15;163(1):204-9. [2]. Takahashi T, et al. A new biotinylating system for DNA using biotin aminocaproyl hydrazide and glutaraldehyde. Nucleic Acids Res. 1989 Jun 26;17(12):4899-900. |
Chemical & Physical Properties
| Density | 1.188 g/cm3 |
|---|---|
| Boiling Point | 777ºC at 760 mmHg |
| Melting Point | 195-196°C |
| Molecular Formula | C16H29N5O3S |
| Molecular Weight | 371.49800 |
| Flash Point | 423.7ºC |
| Exact Mass | 371.19900 |
| PSA | 150.65000 |
| LogP | 2.51840 |
| Vapour Pressure | 4.43E-24mmHg at 25°C |
| Index of Refraction | 1.538 |
| InChIKey | IJJWOSAXNHWBPR-HUBLWGQQSA-N |
| SMILES | NNC(=O)CCCCCNC(=O)CCCCC1SCC2NC(=O)NC21 |
| Storage condition | 2-8°C |
| Water Solubility | DMSO: 25 mg/mL |
Safety Information
| Safety Phrases | S22-S24/25 |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | - |
Articles5
More Articles| Quantitation of glycoproteins on electroblots using the biotin-streptavidin complex. Anal. Biochem. 163 , 204, (1987) A method for the detection and quantitation of glycoproteins on nitrocellulose electroblots is described. Protein mixtures may be solubilized in sodium dodecyl sulfate prior to labeling, which is espe... | |
| Identification of an Atg8-Atg3 protein-protein interaction inhibitor from the medicines for Malaria Venture Malaria Box active in blood and liver stage Plasmodium falciparum parasites. J. Med. Chem. 57(11) , 4521-31, (2014) Atg8 is a ubiquitin-like autophagy protein in eukaryotes that is covalently attached (lipidated) to the elongating autophagosomal membrane. Autophagy is increasingly appreciated as a target in diverse... | |
| Receptor binding activities of biotinylated derivatives of beta-nerve growth factor. J. Neurochem. 46 , 641-648, (1986) beta-nerve growth factor (NGF) was modified by biotinylation via carboxyl group substitution (C-bio-NGF) using biotin hydrazide and the coupling reagent 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide,... |
Synonyms
| biotinamidocaproyl hydrazide |
| MFCD00077659 |
| Biotin LC hydrazide |
