Introduction：Basic information about CAS 24385-10-2|adriamycinone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | adriamycinone |
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| CAS Number | 24385-10-2 | Molecular Weight | 414.36200 |
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| Density | 1.671g/cm3 | Boiling Point | 726.6ºC at 760 mmHg |
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| Molecular Formula | C21H18O9 | Melting Point | 223-225ºC |
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| MSDS | / | Flash Point | 260.4ºC |
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Names
| Name | adriamycinone |
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| Synonym | More Synonyms |
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adriamycinone BiologicalActivity
| Description | Doxorubicinone is a metabolite of an anti-cancer chemotherapy agent Doxorubicin[1]. Doxorubicin is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. |
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| Related Catalog | Research Areas >>Cancer |
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| References | [1]. M Joerger, et al. Pharmacokinetics of low-dose doxorubicin and metabolites in patients with AIDS-related Kaposi sarcoma. Cancer Chemother Pharmacol. 2005 May;55(5):488-96. |
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Chemical & Physical Properties
| Density | 1.671g/cm3 |
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| Boiling Point | 726.6ºC at 760 mmHg |
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| Melting Point | 223-225ºC |
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| Molecular Formula | C21H18O9 |
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| Molecular Weight | 414.36200 |
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| Flash Point | 260.4ºC |
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| Exact Mass | 414.09500 |
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| PSA | 161.59000 |
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| LogP | 0.15390 |
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| Vapour Pressure | 3.7E-22mmHg at 25°C |
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| Index of Refraction | 1.737 |
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| InChIKey | IBZGBXXTIGCACK-CWKPULSASA-N |
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| SMILES | COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)CC(O)(C(=O)CO)CC3O |
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| Storage condition | Amber Vial, -20°C Freezer |
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Synonyms
| 14-hydroxydaunomycinone |
| doxorubicin hydroxyaglycone |
| 8-glycoloyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-5,12-Naphthacenedione |
| Epirubicin aglycone |
| Doxorubicinone |
| Epirubicin aglycon |
| doxorubicin aglycone |
| Adriamycin-aglycon |
| adriamycinaglycone |
| MFCD00871832 |
