CAS 10116-22-0|19-Norpregna-4,9-diene-3,20-dione,17-methyl-

Introduction:Basic information about CAS 10116-22-0|19-Norpregna-4,9-diene-3,20-dione,17-methyl-, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name19-Norpregna-4,9-diene-3,20-dione,17-methyl-
CAS Number10116-22-0Molecular Weight312.44600
Density1.11g/cm3Boiling Point475.5ºC at 760mmHg
Molecular FormulaC21H28O2Melting Point/
MSDS/Flash Point176.6ºC

Names

Namedemegestone
SynonymMore Synonyms

BiologicalActivity

DescriptionDemegestone is an agonist of theprogesterone receptor[1].
Related CatalogResearch Areas >>EndocrinologySignaling Pathways >>GPCR/G Protein >>Glucocorticoid Receptor
References

[1]. Stanczyk FZ, et al. Progestogens used in postmenopausal hormone therapy: differences in their pharmacological properties, intracellular actions, and clinical effects. Endocr Rev. 2013;34(2):171-208.  

Chemical & Physical Properties

Density1.11g/cm3
Boiling Point475.5ºC at 760mmHg
Molecular FormulaC21H28O2
Molecular Weight312.44600
Flash Point176.6ºC
Exact Mass312.20900
PSA34.14000
LogP4.78770
Vapour Pressure3.29E-09mmHg at 25°C
Index of Refraction1.557
InChIKeyJWAHBTQSSMYISL-MHTWAQMVSA-N
SMILESCC(=O)C1(C)CCC2C3CCC4=CC(=O)CCC4=C3CCC21C

Synonyms

Lutionex
Dimegestone
17-Methyl-19-norpregna-4,9-diene-3,20-dione
R2453
R-2459
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