CAS 69942-12-7|N-Boc-DL-serine methyl ester

Introduction：Basic information about CAS 69942-12-7|N-Boc-DL-serine methyl ester, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. N-Boc-DL-serine methyl ester BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	N-Boc-DL-serine methyl ester
CAS Number	69942-12-7	Molecular Weight	219.235
Density	1.1±0.1 g/cm3	Boiling Point	354.3±32.0 °C at 760 mmHg
Molecular Formula	C₉H₁₇NO₅	Melting Point	/
MSDS	/	Flash Point	168.1±25.1 °C

Names

Name	Methyl 2-((tert-butoxycarbonyl)amino)-3-hydroxypropanoate
Synonym	More Synonyms

N-Boc-DL-serine methyl ester BiologicalActivity

Description	N-BOC-DL-serine methyl ester is a Serine derivative. N-BOC-DL-serine methyl ester is used for the synthesis of α,β-dehydro-α-amino acid. N-BOC-DL-serine methyl ester is also used for the synthesis of anti-cancer agent, such as quinazolinone derivative that inhibits PI3K activity, and tricyclic pyrolopyranopyridines that inhibits protein kinase activity[1][2][3].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Others >>Others
References	[1]. Yang Yongqing, et al. Method for synthesizing α,β-dehydro-α-amino acid. Patent CN105037210. [2]. Wu Chengde, et al. Preparation of quinazolinone derivatives useful as PI3Kα inhibitors for the treatment of cancer. Patent WO2019091476. [3]. Pastor Fernandez, et al. Preparation of tricyclic pyrolopyranopyridines as protein kinase inhibitors. Patent WO2017033019.

Description

N-BOC-DL-serine methyl ester is a Serine derivative. N-BOC-DL-serine methyl ester is used for the synthesis of α,β-dehydro-α-amino acid. N-BOC-DL-serine methyl ester is also used for the synthesis of anti-cancer agent, such as quinazolinone derivative that inhibits PI3K activity, and tricyclic pyrolopyranopyridines that inhibits protein kinase activity[1][2][3].

Related Catalog

Research Areas >>CancerSignaling Pathways >>Others >>Others

References

[1]. Yang Yongqing, et al. Method for synthesizing α,β-dehydro-α-amino acid. Patent CN105037210.

[2]. Wu Chengde, et al. Preparation of quinazolinone derivatives useful as PI3Kα inhibitors for the treatment of cancer. Patent WO2019091476.

[3]. Pastor Fernandez, et al. Preparation of tricyclic pyrolopyranopyridines as protein kinase inhibitors. Patent WO2017033019.

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	354.3±32.0 °C at 760 mmHg
Molecular Formula	C₉H₁₇NO₅
Molecular Weight	219.235
Flash Point	168.1±25.1 °C
Exact Mass	219.110672
PSA	88.35000
LogP	0.80
Vapour Pressure	0.0±1.8 mmHg at 25°C
Index of Refraction	1.461
InChIKey	SANNKFASHWONFD-UHFFFAOYSA-N
SMILES	COC(=O)C(CO)NC(=O)OC(C)(C)C
Storage condition	2-8°C

Safety Information

Hazard Codes	Xi

Synonyms

Serine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester

Methyl N-(tert-butoxycarbonyl)serinate

Methyl N-{[(2-methyl-2-propanyl)oxy]carbonyl}serinate

methyl 3-hydroxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate

N-Boc-DL-serine methyl ester

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