CAS 72088-94-9|5(6)-Carboxyfluorescein
| Common Name | 5(6)-Carboxyfluorescein | ||
|---|---|---|---|
| CAS Number | 72088-94-9 | Molecular Weight | 376.32 |
| Density | / | Boiling Point | / |
| Molecular Formula | C21H12O7 | Melting Point | 275 °C |
| MSDS | ChineseUSA | Flash Point | / |
Names
| Name | 5(6)-Carboxyfluorescein |
|---|---|
| Synonym | More Synonyms |
5(6)-Carboxyfluorescein BiologicalActivity
| Description | 5(6)-Carboxyfluorescein contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid; cell-impermeant 5,6-FAM can also be used as a nonfixable polar tracer to investigate fusion, lysis and gap-junctional communication and to detect changes in cell or liposome volume. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersDye ReagentsResearch Areas >>Others |
| References | [1]. Babcock DF. Examination of the intracellular ionic environment and of ionophore action by null point measurements employing the fluorescein chromophore. J Biol Chem. 1983 May 25;258(10):6380-9. [2]. Bonizzoni M, et al. PAMAM dendrimer-induced aggregation of 5(6)-carboxyfluorescein. J Org Chem. 2012 Feb 3;77(3):1258-66. |
Chemical & Physical Properties
| Melting Point | 275 °C |
|---|---|
| Molecular Formula | C21H12O7 |
| Molecular Weight | 376.32 |
| PSA | 226.58000 |
| LogP | 6.72800 |
| InChIKey | BPVHBBXCESDRKW-UHFFFAOYSA-N |
| SMILES | O=C(O)c1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21.O=C(O)c1ccc2c(c1)C1(OC2=O)c2ccc(O)cc2Oc2cc(O)ccc21 |
| Storage condition | Store at 2-8 |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36 |
| Safety Phrases | 37/39-26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| RTECS | CQ7700000 |
| HS Code | 29335995 |
Customs
| HS Code | 29335995 |
|---|
Articles64
More Articles| Characteristics and photo-responsive release property of liposome containing 7-acetoxy coumarin. J. Nanosci. Nanotechnol. 11 , 10262-10270, (2011) A photo-responsive liposome was developed by loading 7-acetoxy coumarin (ATC) in egg phosphatidylcholine (EPC) liposome. ATC was derivetized from 7-hydroxy coumarin using sodium acetate. The ATC-loade... | |
| A novel assay for detecting fusion pore formation: implications for the fusion mechanism. Biochemistry 52(47) , 8510-7, (2013) Membrane fusion is broadly envisioned as a two- or three-step process proceeding from contacting bilayers through one or two semistable, nonlamellar lipidic intermediate structures to a fusion pore. A... | |
| Development of novel diolein-niosomes for cutaneous delivery of tretinoin: influence of formulation and in vitro assessment. Int. J. Pharm. 477(1-2) , 176-86, (2014) This work describes innovative niosomes, composed of diolein alone or in association with the hydrophilic penetration enhancer Labrasol(®), as carriers for cutaneous drug delivery. The model drug was ... |
Synonyms
| Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-5-carboxylic acid, 3',6'-dihydroxy-3-oxo-, compd. with 3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic acid (1:1) |
| 3',6'-Dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-5-carboxylic acid - 3',6'-dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-6-carboxylic acid (1:1) |
| MFCD00151081 |
| Fluoresceincarboxylic Acid |
| EINECS 276-331-1 |
