CAS 7411-49-6|3,3',4,4'-Biphenyltetramine tetrahydrochloride
Introduction：Basic information about CAS 7411-49-6|3,3',4,4'-Biphenyltetramine tetrahydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 3,3',4,4'-Biphenyltetramine tetrahydrochloride | ||
|---|---|---|---|
| CAS Number | 7411-49-6 | Molecular Weight | 360.110 |
| Density | / | Boiling Point | 481.7ºC at 760 mmHg |
| Molecular Formula | C12H18Cl4N4 | Melting Point | 300°C |
| MSDS | ChineseUSA | Flash Point | 282.7ºC |
| Symbol | GHS07, GHS08 | Signal Word | Danger |
Names
| Name | 3,3',4,4'-Biphenyltetramine tetrahydrochloride |
|---|---|
| Synonym | More Synonyms |
BiologicalActivity
| Description | 3,3'-Diaminobenzidine(DAB) is an organic compound that is both chemically and thermodynamically stable; DAB has been used in immunohistochemical staining of nucleic acids and proteins. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersDye ReagentsResearch Areas >>Others |
| References | [1]. Hannetz Roschzttardtz, et al. Plant Cell Nucleolus as a Hot Spot for Iron. |
Chemical & Physical Properties
| Boiling Point | 481.7ºC at 760 mmHg |
|---|---|
| Melting Point | 300°C |
| Molecular Formula | C12H18Cl4N4 |
| Molecular Weight | 360.110 |
| Flash Point | 282.7ºC |
| Exact Mass | 358.028564 |
| PSA | 104.08000 |
| LogP | 7.21520 |
| InChIKey | KJDSORYAHBAGPP-UHFFFAOYSA-N |
| SMILES | Cl.Cl.Cl.Cl.Nc1ccc(-c2ccc(N)c(N)c2)cc1N |
| Water Solubility | Soluble |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 330 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NCIBR* Progress Report for Contract No. NIH-NCI-E-68-1311, Submitted to the National Cancer Institute by Bio-Research Consultants, Inc. (9 Commercial Ave., Cambridge, MA 02141) Volume(issue)/page/year: NCI-E-68-1311,1973 ** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 260 gm/kg/78W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
- REFERENCE :
- JEPTDQ Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC. Volume(issue)/page/year: 2(2),325,1978
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 260 gm/kg/78W-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors
- REFERENCE :
- JEPTDQ Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC. Volume(issue)/page/year: 2(2),325,1978
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 520 gm/kg/78W-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors
- REFERENCE :
- JEPTDQ Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC. Volume(issue)/page/year: 2(2),325,1978
Safety Information
| Symbol | GHS07, GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302-H319-H341-H350 |
| Precautionary Statements | P201-P280-P301 + P312 + P330-P305 + P351 + P338-P308 + P313-P337 + P313 |
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R22;R36/37/38;R40 |
| Safety Phrases | S7-S16-S24-S33-S36/37-S45-S24/25-S22 |
| RIDADR | UN 3316 9/PG 2 |
| WGK Germany | 3 |
| RTECS | DV8753000 |
| Hazard Class | 9.0 |
Articles5
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| The bioanalysis of trastuzumab in human serum using precipitate-enhanced ellipsometry. Anal. Biochem. 393 , 73-79, (2009) For the bioanalysis of therapeutic monoclonal antibodies in biological matrices, immunoassays--especially enzyme-linked immunosorbent assays (ELISAs)--are the most widely used techniques. Although ELI... | |
| Color modification of diaminobenzidine (DAB) precipitation by metallic ions and its application for double immunohistochemistry. J. Histochem. Cytochem. 30 , 1079-1082, (1982) Three metallic ions, NiCl2, CoCl2, and CuSO4, were found to modify the color of the normally brown diaminobenzidine (DAB) reaction. The colors ranged from purplish blue (NiCl2), dark blue/bluish black... |
Synonyms
| DAB TABLET |
| DAB SUBSTRATE |
| DAB-HCL |
| Biphenyl-3,3',4,4'-tetramine tetrahydrochloride |
| DAB TETRAHYDROCHLORIDE |
| DAB |
| 3,3',4,4'-Biphenyltetramine tetrahydrochloride |
| DAB,tetrahydrochloride3 |
| 3,3`-Diaminobenzidine tetrahydrochloride |
| DAB EASY tablets |
| DAB anhydrous |
| MFCD00012969 |
| [1,1'-Biphenyl]-3,3',4,4'-tetramine, hydrochloride (1:4) |
| DAB 4HCL |
| EINECS 231-018-9 |
| DAB WITH METAL ENHANCER |
