CAS 27565-41-9|D-1,4-dithiothreitol

CHEMICAL IDENTIFICATION

RTECS NUMBER :

XO8576500

CHEMICAL NAME :

Threitol, 1,4-dithio-, DL-

CAS REGISTRY NUMBER :

27565-41-9

BEILSTEIN REFERENCE NO. :

1719757

LAST UPDATED :

199806

DATA ITEMS CITED :

8

MOLECULAR FORMULA :

C4-H10-O2-S2

MOLECULAR WEIGHT :

154.26

WISWESSER LINE NOTATION :

SH1YQYQ1SH -DL, THREO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

169 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

333 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

94 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :

DNA inhibition

TEST SYSTEM :

Rodent - rat Liver

DOSE/DURATION :

1 mmol/L

REFERENCE :

ABBIA4 Archives of Biochemistry and Biophysics. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.31- 1951- Volume(issue)/page/year: 166,400,1975 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2950 No. of Facilities: 35 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 627 (estimated) No. of Female Employees: 436 (estimated)